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The mechanism of phenotypic sex differentiation
Arthritis & Rheumatism, 1979AbstractFor the first 2 months of gestation, there is no difference in the development of male and female embryos. Gonadal differentiation then ensues, and the ovary and testis commence to synthesize their characteristic hormones at approximately the same time.
J D, Wilson, J E, Griffin, F W, George
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Molecular Endocrinology of Sex Differentiation
Seminars in Reproductive Medicine, 2002Differentiation of a testis or an ovary from a bipotential gonad is a complex developmental process involving various genes and hormones. Similarly, internal and external genital organs develop from an indeterminate stage from the complex differentiation of Wolffian and Müllerian ducts.
Garry L, Warne, Shankar, Kanumakala
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Unisexual Cucumber Flowers, Sex and Sex Differentiation
2013Sex is a universal phenomenon in the world of eukaryotes. Attempts have been made to understand regulatory mechanisms for plant sex determination by investigating unisexual flowers. The cucumber plant is one of the model systems for studying how sex determination is regulated by phytohormones.
Shu-Nong, Bai, Zhi-Hong, Xu
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Sex Differentials in Health and Mortality
Women & Health, 1987It is common knowledge that females tend to live longer than males. In the United States and most other countries, female death rates are lower than male rates for all age groups and most important causes of death. But while they are alive, females' health seems to be worse than males'.
Lois M. Verbrugge +2 more
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SEX DETERMINATION AND SEX DIFFERENTIATION IN MALARIA PARASITES
Biological Reviews, 1988Summary1. The most coherent body of information on the malarial life‐cycles comes from studies on P. berghei and P. falciparum. For both species there is an extensive and accurate description of the life‐cycle available based on synchronized in‐vitro and in‐vivo infections (the latter only for P. berghei).2. The trophozoites preceding the young gamonts
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Genetic mechanisms of sex differentiation
Current Opinion in Pediatrics, 1996Cloning of the SRY sex-determining locus on the Y chromosome has stimulated research on the genetic mechanisms of sex determination. It now appears that SRY is not the only gene required for testicular differentiation; X-linked and autosomal genes are also important.
N, Josso, R, Rey
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Genetic Disorders of Sex Differentiation
2011Disorders of sex development (DSD) constitute a large array of disorders that affect the genito-urinary tract and often include the endocrine system [25]. 46,XY DSD includes 46,XY complete or partial gonadal dysgenesis and undervirilization or undermasculinization of an XY male due to defects in androgen synthesis or action.
Ken, McElreavey, Anu, Bashamboo
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[Sex determination and sex differentiation].
Die Naturwissenschaften, 1981Sex determination in mammals proceeds like a cascade from the level of the sex chromosomes to the gonads, to the genital ducts, and finally to the expression of the male or female phenotype. At the level of the genital ducts male sex organs are induced by testosterone. Its action depends on an intact cytoplasmic androgen receptor protein.
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Sex Differentiation: Organizing Effects of Sex Hormones
2013Men and women differ, not only in their anatomy but also in their behavior. Research using animal models has convincingly shown that sex differences in the brain and behavior are induced by sex hormones during a specific, hormone-sensitive period during early development.
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Chromosomes and sex differentiation in eutherians
Development, 1984ABSTRACT In order to learn more about the role of sex chromosome-dependent gene products in gonadogenesis, changes in protein patterns were studied during gonadal development. Two-dimensional gel electrophoresis analysis revealed specific proteins in both sexes at all developmental stages.
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