Results 51 to 60 of about 2,126,536 (362)
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
Impact of a theoretically based sex education programme (SHARE) delivered by teachers on NHS registered conceptions and terminations: final results of cluster randomised trial [PDF]
<b>Objective</b>: To assess the impact of a theoretically based sex education programme (SHARE) delivered by teachers compared with conventional education in terms of conceptions and terminations registered by the NHS.
Abraham, C.+6 more
core +3 more sources
The present paper aims at providing a portrait of Paolo Mantegazza as educator and hygienist. With the publication of his popular almanacs on hygiene, that started in 1866, and following the precepts of what we might call "scientific pedagogy ...
Matteo Loconsole
doaj +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
DEFENDING ALL-MALE EDUCATION: A NEW CULTURAL MOMENT FOR A RENEWED DEBATE [PDF]
Although all-female schools still prosper and are defended by members of the academic elite, an all-male college has become a near-extinct species. Many people are surprised such a creature still exists.
Webb, Stephen H.
core +1 more source
Parents as agents of informal sex education: what to do?
This article was born out of the numerous conversations of the author with parents over the past five years and discussions about educational articles. In the article, the reader is offered a short historical overview of the conditions in which a certain
Marina Travkova
doaj
Quantifying disparities in air pollution exposures across the United States using home and work addresses [PDF]
While human mobility plays a crucial role in determining air pollution exposures and health risks, research to-date has assessed risks based solely on residential location. Here we leveraged a database of ~ 130 million workers in the US and published PM2.5 data between 2011-2018 to explore how incorporating information on both workplace and residential
arxiv
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna+4 more
wiley +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
The Impact of Abstinence-Only Sex Education Programs in the United States on Adolescent Sexual Outcomes [PDF]
Though there are many evaluations of abstinence-only sex education programs in the United States, there is a relatively small body of literature exploring the programs’ impact specifically on adolescent sexual behavior.
Heels, Sonja W.
core +2 more sources