Results 201 to 210 of about 3,086,991 (246)
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Effects of oestradiol on sex hormone binding globulin
Acta Endocrinologica, 1982Abstract. Sex hormone binding globulin (SHBG) levels were studied for possible effects of oestradiol-17β on SHBG. No change in SHBG plasma was recorded during normal menstrual cycles or during treatment with oestradiol-17β to menopausal women. However, gonadotrophin treatment to amenorrhoeic women to induce ovulation resulted in high oestradiol ...
V, Odlind +4 more
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Trends in Endocrinology and Metabolism, 2021
Over the past decade, there have been important breakthroughs in our understanding of the regulation and function of sex hormone-binding globulin (SHBG). A recent genome-wide association and Mendelian randomization study has provided new insights at the population level.
Simons, Pomme I. H. G. +3 more
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Over the past decade, there have been important breakthroughs in our understanding of the regulation and function of sex hormone-binding globulin (SHBG). A recent genome-wide association and Mendelian randomization study has provided new insights at the population level.
Simons, Pomme I. H. G. +3 more
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Sex Hormone Binding Globulin in Clinical Perspective
Acta Obstetricia et Gynecologica Scandinavica, 1987The plasma steroid‐binding proteins play a fundamental role in the modification and delivery of the steroid “signal” to its target tissue. While their precise function requires further evaluation, the measurement of these proteins, particularly of SHBG, provides clinically useful information.This article reviews the current theories of sex steroid ...
A, Bond, C, Davis
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Clinical Endocrinology, 1974
A review was made to understand how plasma binding protein might influence sex-hormone action in target tissues. Steroids are predominately bound to plasma proteins and only unbound steroids enter the cells. Sex-hormone-binding globulin (SHBG) binds to both the main circulating steroid T and E2 but changes in SHBG concentrations exert significant ...
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A review was made to understand how plasma binding protein might influence sex-hormone action in target tissues. Steroids are predominately bound to plasma proteins and only unbound steroids enter the cells. Sex-hormone-binding globulin (SHBG) binds to both the main circulating steroid T and E2 but changes in SHBG concentrations exert significant ...
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Sex Hormone Binding Globulin in Carcinoma of the Prostate
British Journal of Urology, 1977Sex Hormone Binding Globulin (SHBG) was measured in 130 patients with carcinoma of the prostate. Its level is raised in patients treated with oestrogen and it is possible that this may be of prognostic significance. The possible relevance of SHBG in oestrogen-treated patients is discussed.
A L, Houghton, R, Turner, E H, Cooper
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Sex hormone-binding globulin in gestational diabetes
Acta Obstetricia et Gynecologica Scandinavica, 2000Insulin is an important regulator of serum sex hormone-binding globulin (SHBG) concentration which works by inhibiting its production in hepatocytes. Low SHBG level is associated with increased insulin resistance and hyperinsulinemia. Our purpose was to compare maternal serum SHBG level between normal and gestational diabetic pregnant women and to ...
J L, Bartha +3 more
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Dexamethasone suppresses sex-hormone binding globulin
Fertility and Sterility, 1988Dexamethasone suppression (DEX-S) for 14 days has been used to determine the probable source of androgen excess. The exact mechanism(s) of DEX-S is still unclear. The authors postulated that dexamethasone (DEX) inhibits either the synthesis or secretion of sex-hormone binding globulin (SHBG). To examine this hypothesis, 14 women with polycystic ovarian
R E, Blake +3 more
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Are Corticosteroid‐Binding Globulin and Sex Hormone‐Binding Globulin Hormones?a
Annals of the New York Academy of Sciences, 1988Because it no longer seemed reasonable to us that the sole function of the steroid-binding proteins in plasma was to serve as a buffer reservoir for steroid hormones, we conducted experiments which sought out other possibilities. Both CBG and SHBG bind to cell membranes, and this interaction partakes of the general characteristics of peptide hormone ...
W, Rosner +4 more
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European Journal of Applied Physiology and Occupational Physiology, 1996
The response of total testosterone (T), free testosterone (fT), sex hormone-binding globulin (SHBG) and non-SHBG-bound testosterone (NST) to the same exercise protocol was evaluated in two different experiments on long distance runners. The first experiment was performed in the morning at 0900 hours with nine athletes, while the second was carried out ...
Bonifazi M., Lupo C.
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The response of total testosterone (T), free testosterone (fT), sex hormone-binding globulin (SHBG) and non-SHBG-bound testosterone (NST) to the same exercise protocol was evaluated in two different experiments on long distance runners. The first experiment was performed in the morning at 0900 hours with nine athletes, while the second was carried out ...
Bonifazi M., Lupo C.
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Free estradiol and sex hormone-binding globulin
Steroids, 2015SHBG is a plasma protein that participates in the regulation of free estradiol and free testosterone in plasma. We discuss the concept of the nature of a free estradiol and how best to ascertain its value. It can be measured or calculated; the ways in which this can be done are explored along with the advantages and disadvantages of each.
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