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The European Journal of Contraception & Reproductive Health Care, 1997
The effects of steroidal hormones on sexual desire and motivation are a question still under debate. This paper reviews up-to-date knowledge regarding physiological imprinting and activation by endogenous hormones of central nervous system areas involved in libido during intrauterine life and puberty.
M, Dei, A, Verni, L, Bigozzi, V, Bruni
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The effects of steroidal hormones on sexual desire and motivation are a question still under debate. This paper reviews up-to-date knowledge regarding physiological imprinting and activation by endogenous hormones of central nervous system areas involved in libido during intrauterine life and puberty.
M, Dei, A, Verni, L, Bigozzi, V, Bruni
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Biological Psychiatry, 2015
Psychiatric illness is not an “equal opportunity” disease. For example, the lifetime prevalence of posttraumatic stress disorder (PTSD) is twice as high in women than in men. In recent years, gonadal steroids have moved into the spotlight as a potential key to understanding this sex difference in vulnerability to trauma-related and stress-related ...
Naomi Nagaya, Stephen Maren
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Psychiatric illness is not an “equal opportunity” disease. For example, the lifetime prevalence of posttraumatic stress disorder (PTSD) is twice as high in women than in men. In recent years, gonadal steroids have moved into the spotlight as a potential key to understanding this sex difference in vulnerability to trauma-related and stress-related ...
Naomi Nagaya, Stephen Maren
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Annals of the New York Academy of Sciences, 2003
Abstract: The central nervous system (CNS) is one of the main target tissues for sex steroid hormones, which act both through genomic mechanisms, modulating synthesis, release, and metabolism of many neuropeptides and neurotransmitters, and through nongenomic mechanisms, influencing electrical excitability, synaptic function, and morphological ...
BERNARDI F +4 more
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Abstract: The central nervous system (CNS) is one of the main target tissues for sex steroid hormones, which act both through genomic mechanisms, modulating synthesis, release, and metabolism of many neuropeptides and neurotransmitters, and through nongenomic mechanisms, influencing electrical excitability, synaptic function, and morphological ...
BERNARDI F +4 more
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Sex Steroids in Autoimmune Diseases
Current Topics in Medicinal Chemistry, 2011A sexual dysmorphism in the immune response has been described and females display an increased incidence of autoimmune diseases. Experimental data show that sex steroids influence immune cell development and have immunomodulatory effects. The distribution, the action (genomic and nongenomic), the sex and tissue-depending expression pattern of estrogen,
A. MARTOCCHIA +3 more
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Medicine & Science in Sports & Exercise, 2023
Biological sex is a primary determinant of athletic performance because of fundamental sex differences in anatomy and physiology dictated by sex chromosomes and sex hormones.
Sandra K. Hunter +9 more
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Biological sex is a primary determinant of athletic performance because of fundamental sex differences in anatomy and physiology dictated by sex chromosomes and sex hormones.
Sandra K. Hunter +9 more
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Clinical Oncology, 1997
The conventional two-step theory of carcinogenesis suggests that malignant transformation is initiated as a genetic event and then promoted to emerge as a clinical disease by constitutional factors within the internal environment of the host. There has been much excitement recently in breast cancer research following the description of two genes (BRCA1,
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The conventional two-step theory of carcinogenesis suggests that malignant transformation is initiated as a genetic event and then promoted to emerge as a clinical disease by constitutional factors within the internal environment of the host. There has been much excitement recently in breast cancer research following the description of two genes (BRCA1,
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Biochemical Pharmacology, 2017
The brain has long been known as a dimorphic organ and as a target of sex steroids. It is also a site for their synthesis. Sex steroids in numerous ways can modify cerebral physiology, and along with many processes adult neurogenesis is also modulated by sex steroids.
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The brain has long been known as a dimorphic organ and as a target of sex steroids. It is also a site for their synthesis. Sex steroids in numerous ways can modify cerebral physiology, and along with many processes adult neurogenesis is also modulated by sex steroids.
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Obstetrics and Gynecology Clinics of North America, 1987
Hormones, particularly estrogens, have been suspected for many years of being carcinogens. Retrospective studies from the mid-1970s indicate that unopposed estrogen replacement therapy increases the risk for endometrial cancer. However, recent reports have failed to incriminate even unopposed estrogens for any significantly increased risk of breast ...
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Hormones, particularly estrogens, have been suspected for many years of being carcinogens. Retrospective studies from the mid-1970s indicate that unopposed estrogen replacement therapy increases the risk for endometrial cancer. However, recent reports have failed to incriminate even unopposed estrogens for any significantly increased risk of breast ...
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Physiological Reviews, 2001
Sex steroids are essential for skeletal development and the maintenance of bone health throughout adult life, and estrogen deficiency at menopause is a major pathogenetic factor in the development of osteoporosis in postmenopausal women. The mechanisms by which the skeletal effects of sex steroids are mediated remain incompletely understood, but in ...
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Sex steroids are essential for skeletal development and the maintenance of bone health throughout adult life, and estrogen deficiency at menopause is a major pathogenetic factor in the development of osteoporosis in postmenopausal women. The mechanisms by which the skeletal effects of sex steroids are mediated remain incompletely understood, but in ...
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