Results 51 to 60 of about 2,236,961 (400)

Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]

, 2016
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia, Lara, H. E., Recabarren, S. E., Roselli, C. E., Zubeldia Brenner, Lautaro   +4 more
core   +2 more sources

Hippocampal synthesis of sex steroids and corticosteroids: essential for modulation of synaptic plasticity

Frontiers in Endocrinology, 2011
Sex steroids play essential roles in the modulation of synaptic plasticity and neuroprotection in the hippocampus. Accumulating evidence shows that hippocampal neurons synthesize both estrogen and androgen.
Yasushi eHojo, Yasushi eHojo, Yasushi eHojo, Shimpei eHigo, Suguru eKawato, Suguru eKawato, Suguru eKawato, Yusuke eHatanaka, Yuuki eOoishi, Gen eMurakami, Gen eMurakami, Hirotaka eIshii, Yoshimasa eKomatsuzaki, Yoshimasa eKomatsuzaki, Mari eOgiue-Ikeda, Hideo eMukai, Hideo eMukai, Hideo eMukai, Tetsuya eKimoto, Tetsuya eKimoto, Tetsuya eKimoto   +20 more
doaj   +1 more source

Autophagy regulates sex steroid hormone synthesis through lysosomal degradation of lipid droplets in human ovary and testis

Cell Death and Disease, 2023
Autophagy is an evolutionarily conserved process that aims to maintain the energy homeostasis of the cell by recycling long-lived proteins and organelles.
Yashar Esmaeilian, Francesko Hela, Gamze Bildik, Ece İltumur, Sevgi Yusufoglu, Ceren Sultan Yildiz, Kayhan Yakin, Yakup Kordan, Ozgur Oktem   +8 more
doaj   +1 more source

Sex steroid hormones in relation to Barrett’s esophagus: An analysis of the FINBAR Study [PDF]

, 2017
Previously we observed strong positive associations between circulating concentrations of free testosterone and free dihydrotestosterone (DHT) in relation to Barrett’s esophagus in a US male military population.
Abnet, Christian C, Anderson, Lesley A, carson, Patrick, Cook, M. B., Dawsey, Sanford M, Drahos, Jennifer, Falk, Roni T, Guillemette, Chantal, Hyland, Paula L, Murray, Liam J, Pfeiffer, Ruth, Taylor, Philip R, Wood, Sharon   +12 more
core   +1 more source

Sex-Specific Causal Relations between Steroid Hormones and Obesity—A Mendelian Randomization Study

Metabolites, 2021
Steroid hormones act as important regulators of physiological processes including gene expression. They provide possible mechanistic explanations of observed sex-dimorphisms in obesity and coronary artery disease (CAD).
Janne Pott, Katrin Horn, Robert Zeidler, Holger Kirsten, Peter Ahnert, Jürgen Kratzsch, Markus Loeffler, Berend Isermann, Uta Ceglarek, Markus Scholz   +9 more
doaj   +1 more source

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]

, 2010
Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt, Bebia, Chang, de Morais, Dominique Maiter, Dorota Tomalik-Scharte, Fl  ck, Fuhr, Gomes, Hannah E Ivison, Henderson, Jetter, Julia Kirchheiner, Kelley, Kirchheiner, Kranendonk, Nebert, Nicolo, Parkinson, Porter, Ribes, Sachse, Tantcheva-Po  r, Tomalik-Scharte, Uwe Fuhr, Wiebke Arlt   +25 more
core   +2 more sources

Sex Steroids and Sex Chromosomes at Odds? [PDF]

Endocrinology, 2005
Alfred Jost’s proposal in the 1940s (1) that testes are crucial for the development of the male phenotype, and that without them the body develops in a female direction, has been driving research in the field of sexual differentiation for more than half a century.
openaire   +2 more sources

Effects of steroid hormones on lipid metabolism in sexual dimorphism: A Mendelian randomization study

Frontiers in Endocrinology, 2023
BackgroundAlthough the role of steroid hormones in lipid levels has been partly discussed in the context of separate sexes, the causal relationship between steroid hormones and lipid metabolism according to sex has not been elucidated because of the ...
Junzhi Liang, Bowen Zhang, Yannan Hu, Zhijing Na, Zhijing Na, Da Li, Da Li, Da Li   +7 more
doaj   +1 more source

Microbial degradation of steroid sex hormones: implications for environmental and ecological studies

Microbial Biotechnology, 2019
Steroid hormones modulate development, reproduction and communication in eukaryotes. The widespread occurrence and persistence of steroid hormones have attracted public attention due to their endocrine‐disrupting effects on both wildlife and human beings.
Yin-Ru Chiang, S. Wei, Pong Wang, Pei-Hsun Wu, Chang-Ping Yu   +4 more
semanticscholar   +1 more source

3D model of amphioxus steroid receptor complexed with estradiol [PDF]

, 2009
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
David J. Chang, Michael E. Baker
core   +2 more sources