Results 51 to 60 of about 420,913 (305)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

No strings attached: a mixed methods evaluation of the acceptability of the San Francisco Abundant Birth Project, a perinatal guaranteed income program

BMC Public Health
Background Economic insecurity during pregnancy is a critical social determinant of maternal and infant health. Traditional public assistance programs often fail to meet the needs of marginalized communities, particularly Black and Pacific Islander ...
Monica M. De La Cruz, Stephanie Arteaga, Erin M. Hubbard, Reiley D. Reed, Wyconda Cotton-Curtis, Michaela Taylor, Breezy Powell, Anjeanette Coats, Sabra Bell, Payshia Edwards, Maile Chand, Troy Roberts, Brittany Chambers Butcher, Deborah Karasek, Zea Malawa, Anu Manchikanti Gomez   +15 more
doaj   +1 more source

Population and Reproductive Health [PDF]

, 2009
Outlines the foundation's grantmaking strategies to reduce maternal mortality and morbidity and to advance youths' sexual and reproductive health and rights.

core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A socio-ecological analysis of factors influencing HIV treatment initiation and adherence among key populations in Papua New Guinea

BMC Public Health, 2021
Background In Papua New Guinea (PNG) members of key populations, including female sex workers (FSW), men who have sex with men (MSM) and transgender women (TGW), have higher rates of HIV compared to the general adult population and low engagement in HIV ...
Elke Mitchell, Avi Hakim, Somu Nosi, Martha Kupul, Ruthy Boli-Neo, Herick Aeno, Michelle Redman-Maclaren, Sophie Ase, Angelyn Amos, Parker Hou, Rebecca Narokobi, Barne Willie, Andrew J. Vallely, John M. Kaldor, Steven G. Badman, Angela Kelly-Hanku   +15 more
doaj   +1 more source

Re-Costing Cairo: Revised Estimate of the Resource Requirements to Achieve the ICPD Goals [PDF]

, 2009
Achieving universal access to reproductive health, including family planning services and supplies, is essential to ensuring the health and well-being of women and their families.
Suzanna Dennis
core  

Attitudes of Icelandic young people toward sexual and reproductive health services [PDF]

, 1999
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldCONTEXT: Iceland has higher levels of fertility among both adult women and adolescents than many other western European countries.
Bender, S S
core   +1 more source

Repoliticising sexual and reproductive health and rights [PDF]

Reproductive Health Matters, 2011
This editorial explores what is happening globally towards achieving sexual and reproductive health and rights. It discusses the perceived fragmentation of work in this field and the de-politicization of the process and the goals involved as the number of issues groups and networks involved has burgeoned.
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source