Results 81 to 90 of about 420,913 (305)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Providing technical assistance: lessons learned from the first three years of the WHO Adolescent and Youth Sexual and Reproductive Health and Rights Technical Assistance Coordination Mechanism

open access: yesReproductive Health
Young people’s sexual and reproductive health (SRH) continues to be a major challenge in low and middle-income countries, with implications for public health now and in the future. Fortunately there is a growing array of evidence-based interventions, and
Bruce Dick   +5 more
doaj   +1 more source

The Impact of Early Abuse on Male Sexual and Reproductive Health [PDF]

open access: yes, 2008
With this resource guide, Healthy Teen Network strives to draw attention to the significant issue of abuse for males; add to the voices calling for a shift in our thinking about males and sexual abuse; and call for parity in education, services and ...

core  

Adolescent pregnancies and girls' sexual and reproductive rights in the amazon basin of Ecuador: an analysis of providers' and policy makers' discourses [PDF]

open access: yes, 2010
Background: Adolescent pregnancies are a common phenomenon that can have both positive and negative consequences. The rights framework allows us to explore adolescent pregnancies not just as isolated events, but in relation to girls' sexual and ...
Isabel Goicolea   +3 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Effect of PLISSIT model counseling on the sexual quality of life of infertile women: a randomized controlled trial

open access: yesScientific Reports
Infertility can lead to sexual dysfunction and can have negative effects on sexual quality of life in women. The present study was conducted to determine the effect of PLISSIT model counseling on the sexual quality of life of infertile women with sexual ...
Reyhane Amini   +2 more
doaj   +1 more source

Does sex education influence sexual and reproductive behaviour of women? Evidence from Mexico [PDF]

open access: yes
This article examines the influence of sex education on sexual and reproductive behavior in Mexican women. Exposure to in-school sex education is identified and duration-hazard models are estimated to assess its effects on initiation of sexual activity ...
Pamela Ortiz Arévalo
core  

The Association between Knowledge and Attitude, in Reproductive Health and Sexual Behavior in Female Adolescents, Banda Aceh [PDF]

open access: yes, 2018
Background: More than a quarter of the world’s population is between the ages of 10 and 24, with 86% living in less developed countries. These young people are tomorrow’s parents. Reproductive health is important for adolescents.
Akmal, R. (Rianda)   +2 more
core  

Adolescent Reproductive Knowledge, Attitudes, and Beliefs and Future Fatherhood. [PDF]

open access: yes, 2016
PurposeWith a growing focus on the importance of men's reproductive health, including preconception health, the ways in which young men's knowledge, attitudes, and beliefs (KAB) predict their reproductive paths are understudied.
Adam, Emma K   +7 more
core   +2 more sources

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