Results 41 to 50 of about 74,218 (307)
Sexual selection in a transparent worm : insights from fluorescent sperm [PDF]
, 2015 Sexual selection is a potent source of selection underlying the evolution of sexual dimorphism, reproductive strategies and mating systems. Although sexual selection was initially thought to occur exclusively at the pre-copulatory stage (e.g., contests ...
Marie-Orleach, Lucas
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Sexual behavior and testis morphology in the BACHD rat model. [PDF]
PLoS ONE, 2018 BACKGROUND:Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin (HTT) gene, which results in brain neurodegeneration and peripheral pathology affecting different organs including testis ...
Arianna Novati +4 more
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Frontiers in Neuroscience, 2023 IntroductionAdverse early life experiences affect neuronal growth and maturation of reward circuits that modify behavior under reward predicting conditions.
Ermis Ryakiotakis +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Sex, Aggression, and Pain: Sociobiological Implicatios for Theological Anthropology
Zygon, 1998 Theological anthropology can be enriched by paying attention to insights into human behavior taken from sociobiology. The capacity for reflective self‐consciousness enables the human animal to respond to basic instincts and drives in unprecedented ways.
doaj +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Animal models for bipolar disorder: from bedside to the cage
International Journal of Bipolar Disorders, 2017 Bipolar disorder is characterized by recurrent manic and depressive episodes. Patients suffering from this disorder experience dramatic mood swings with a wide variety of typical behavioral facets, affecting overall activity, energy, sexual behavior ...
Dominik K. E. Beyer, Nadja Freund
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Evolutionary pets: offspring numbers reveal speciation process in domesticated chickens. [PDF]
PLoS ONE, 2012 Since Darwin, the nature of the relationship between evolution and domestication has been debated. Evolution offers different mechanisms of selection that lead to adaptation and may end in the origin of new species as defined by the biological species ...
Inga Tiemann, Gerd Rehkämper
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source