Results 31 to 40 of about 88,631 (252)
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa +7 more
wiley +1 more source
Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex +13 more
wiley +1 more source
Male or female? Brains are intersex
The underlying assumption in popular and scientific publications on sex differences in the brain is that human brains can take one of two forms male or female, and that the differences between these two forms underlie differences between men and women in
Daphna eJoel
doaj +1 more source
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol +6 more
wiley +1 more source
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver +25 more
wiley +1 more source
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
Optimizing egg production by trait selection and starvation in Hydra vulgaris
Hydra vulgaris is considered an effectively immortal freshwater cnidarian. As a sister group to all Bilateria, studies of cnidarian genomes offer valuable evolutionary insight into a range of genetic mechanisms.
Kelso N. Cochran +3 more
doaj +1 more source
ENDOCRINAL DISORDERS: ETIOLOGY AND PATHOGENESIS. DYSFUNCTIONS OF THE SEXUAL GLANDS
The issues of etiology, pathogenesis, clinical manifestations and development mechanisms of the most common forms of endocrinalregulation of the sexual glands, impairments of the puberty in girls and boys and sexual dysfunction in women and men are ...
P. F. Litvitskii
doaj +1 more source
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
The bearded dragon (Pogona vitticeps) is the most commonly kept pet lizard and a promising model organism for studies of sex determination and gonadal development.
Izabela Rams-Pociecha +2 more
doaj +1 more source

