Results 61 to 70 of about 98,247 (293)

Gonadoblastoma in a patient with 46, XY complete gonadal dysgenesis

open access: yesThe Turkish Journal of Pediatrics, 2016
46, XY complete gonadal dysgenesis (Swyer syndrome) is a rare cause of 46, XY sexual development disorder. The patient presented to our clinic with absence of breast development and lack of periods at the age of 17 years.
Melikşah Keskin   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Indicators of physiological stress and the elaboration of sexual traits in the collared flycatcher

open access: yes, 2006
Stress may have consequences for the evolution of condition-dependent sexual traits. For example, stress may be related to sexual traits through immune function, and sexual traits can reflect how individuals bear the costs of stress-mediated ...
Török, János   +12 more
core   +1 more source

Analysis of Sogatella furcifera (Horvath) soluble proteins by SDS-PAGE [PDF]

open access: yesArthropods, 2016
The soluble proteins from nymphs and adults of Sogatella furcifera were analyzed by SDS-PAGE. The number of protein bands increased gradually as the nymphs developing, such as six and 14 protein bands were found in 3rd-instar nymphs and 5th-instar nymphs
ZiQiang Liang   +2 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A comparative, developmental and clinical perspective of neurobehavioral sexual dimorphisms

open access: yesFrontiers in Neuroscience, 2012
Neurobiological mechanisms involved in sexual differentiation of the central nervous system will be presented with a comparative view across vertebrates.
Maria-Paz eViveros   +10 more
doaj   +1 more source

Differentiation of sexual behaviour in pigs [PDF]

open access: yesBioscientifica Proceedings, 2020
Behaviour in pigs is sexually dimorphic as early as 1 month of age; mounting of penmates is observed more frequently for males than for females. This mounting reaches its highest frequency during the 2nd month of life and then declines to a low frequency in prepubertal pigs.
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Locally adapted fish populations maintain small-scale genetic differentiation despite perturbation by a catastrophic flood event [PDF]

open access: yes, 2010
Background: Local adaptation to divergent environmental conditions can promote population genetic differentiation even in the absence of geographic barriers and hence, lead to speciation.
Tiedemann, Ralph   +27 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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