Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang +13 more
wiley +1 more source
Transvaginal sacrospinous ligament fixation: Efficacy in treating pelvic prolapse and influence on patients' anxiety and depression. [PDF]
Zhang RR +4 more
europepmc +1 more source
SSI Prize Essay for Female Sexual Dysfunction—Clinical ‘Clinical evaluation of female sexual function: effects of age and estrogen status on subjective and physiologic sexual responses’ [PDF]
JR Berman +5 more
openaire +1 more source
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang +13 more
wiley +1 more source
A digital health intervention: development and validation of a social media nursing program for sexual dysfunction following cervical cancer radical hysterectomy. [PDF]
Huang C, Qiu Y, Huang X, Tang H.
europepmc +1 more source
Single potential analysis of cavernous electric activity [PDF]
C. G. Stief +18 more
core +1 more source
Metal content determination of some sexual dysfunction medicine samples in northern Nigeria
A. Samali +3 more
semanticscholar +1 more source
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu +7 more
wiley +1 more source
Sexual dysfunction in women who received breast cancer treatment: a cross-sectional study. [PDF]
Guedes TSR +9 more
europepmc +1 more source

