Results 41 to 50 of about 48,926 (304)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Sexual Dysfunctions among Diabetic and Non-diabetic

open access: yesJournal of Nepal Health Research Council
Background: Sexual dysfunctions including erectile dysfunction among men, a widespread sexual health issue, pose challenges to sexual satisfaction. This cross-sectional study aimed to assess the prevalence and determinants of sexual dysfunctions in both
Khem Bahadur Karki   +2 more
doaj   +1 more source

Sexual orientation and drive: a comparative pilot study on sexual desire [PDF]

open access: yes, 2017
Many studies addressing sexual drive and hypersexuality stated that homosexuals are used to report higher levels of sexual desire and compulsive sexual behaviors. Literature showed a lack of comparisons between perceived level of desire in hetero and gay
Nimbi, Filippo Maria   +3 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Societal Influences on Sexual Dysfunctions: The Clinical Sociologist as Sex Educator [PDF]

open access: yes, 1985
The traditional psychoanalytic approach to sexual dysfunctions deemphasizes societal factors as contributing to sexual dysfunctions The new approach to sex therapy, which has developed since 1970, emphasizes a diversity of factors, including societal ...
Lavender, Abraham D.
core   +1 more source

Thyroid hormone receptors and ligand, tissue distribution and sexual behavior [PDF]

open access: yes, 2018
The thyroid hormones (THs) triiodothyronine (T3) and tetraiodothyronine, or thyroxine (T4), not only dramatically impact on development and differentiation, but also on the sexual and reproductive function.
Carosa, E, Jannini, Ea, Lenzi, A
core   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

Psychosexual disorders and dermatologists

open access: yesIndian Dermatology Online Journal, 2016
Sexual problems that are psychological in origin, rather than physiological, are called psychosexual disorders. Multiple factors, such as general health of the patient, chronic illnesses, psychiatric/psychological disorders, and socio-cultural factors ...
Tarun Narang, Garima, Shubh M Singh
doaj   +1 more source

Androgens and Female Sexuality: Molecular Insights, Neuroendocrine Crosstalk and Future Therapeutic Directions

open access: yesClinical and Experimental Obstetrics & Gynecology, 2023
Objective: The scientific community has recently directed its attention towards investigating the role of androgens in female sexuality. This narrative review aims to elucidate the central and peripheral androgen-mediated mechanisms involved in female ...
Giulia Montan   +11 more
doaj   +1 more source

Is “Unconsummated Marriage” still an appropriate term? A snapshot of reality [PDF]

open access: yes, 2016
The most shared definition of Unconsummated Marriage (UM) refers to “the failure to perform successful sexual intercourse at the beginning of the marriage.
Fabrizi, A   +5 more
core  

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