Results 61 to 70 of about 48,926 (304)

The Abduction of Disorder in Psychiatry [PDF]

, 1999
The evolutionary cornerstone of J. C. Wakefield's (1999) harmful dysfunction thesis is a faulty assumption of comparability between mental and biological processes that overlooks the unique plasticity and openness of the brain?s functioning design.
Hinshaw, Stephen P., Richters, John E.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Multidimensional sexual perfectionism and female sexual function: A longitudinal investigation [PDF]

, 2016
Research on multidimensional sexual perfectionism differentiates four forms of sexual perfectionism: self-oriented, partner-oriented, partner-prescribed, and socially prescribed.
AM Habke, American Psychiatric Association, B Butzer, British Psychological Society, BW McCarthy, C Crisp, CE Landa, CM Dundon, GL Flett, HC Yeh, HFL Meyer-Bahlburg, J Cohen, J Simons, J Stoeber, J Stoeber, J Stoeber, J Stoeber, J Stoeber, J Stoeber, J Stoeber, JGH Dunn, JL Shifren, Joachim Stoeber, KR Giles, Laura N. Harvey, LS Aiken, MC Quadland, MP McCabe, MW Enns, O Kobori, PA Frazier, PL Hewitt, PL Hewitt, PL Hewitt, PM DiBartolo, R Basson, RJ Eidelson, RO Frost, RO Frost, SD Gosling, SJ Egan, SL Davison, TW Taris, WE Snell Jr, WE Snell Jr   +44 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Breaking the Taboo: Unveiling the Prevalence and Predictors of Female Sexual Dysfunction in Tunisia

European Psychiatry
Introduction Female sexuality is a complex and multifactorial domain that can be influenced by a variety of psychological, biological, relational, and sociocultural factors.
K. Razki, A. Larnaout, C. Najar, S. Ben Aissa, R. Lansari, W. Melki   +5 more
doaj   +1 more source

Biology of Sexual Dysfunction [PDF]

, 2009
Sexual activity is a multifaceted activity, involving complex interactions between the nervous system, the endocrine system, the vascular system and a variety of structures that are instrumental in sexual excitement, intercourse and satisfaction.
Goyal, N, MN, Anil Kumar, Pai, NB, Rao, S, Rao, TSS   +4 more
core  

Are Hand Preference and Sexual Orientation Possible Predicting Factors for Finasteride Adverse Effects in Male Androgenic Alopecia? [PDF]

, 2016
Sexual side effects of finasteride seem to be redoubtable, being encountered not only during therapy but also after treatment cessation. Consequently, any possible clinical/paraclinical elements that might predict these adverse effects would be useful in
Berglund, Hu, Irwig, Mondaini, Motofei, Motofei, Motofei, Savic, Savic   +8 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Sexuality of women aged 60+ with hypertension

Journal of Education, Health and Sport
Introduction Sexuality of people aged 60+ is a sphere that presents many challenges. Special attention should be paid to media messages that mainly glorify 'young and beautiful' individuals. There is little focus on the sexuality of seniors, alongside a
Agnieszka Pawełko, Maria Ciechacka, Ewelina Bąk   +2 more
doaj   +1 more source

Female Sexual Dysfunctions and Urogynecological Disorders [PDF]

European Medical Journal Urology, 2013
Female sexual dysfunctions are a highly prevalent and often-underestimated health problem and include disorders of sexual desire, arousal, orgasm and sexual pain, associated with self-distress. Pathophysiology of female sexual dysfunctions is complex and
Emillio Sacco, Daniele Tienforti
doaj