Results 51 to 60 of about 927,971 (300)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reduced treatment-emergent sexual dysfunction as a potential target in the development of new antidepressants [PDF]

, 2013
Pleasurable sexual activity is an essential component of many human relationships, providing a sense of physical, psychological, and social well-being.
Masdrakis, V.G., Palazzo, M.C., Baldwin, D.S.   +2 more
core   +1 more source

Sexual dysfunctions following sphincter-preserving rectal resection

, 2015
Increase in number of sphincter-preserving rectal resections for carcinoma, as well as improved patient survival brings to the fore the question relating to quality of patient's life also in the sense of influencing their sexual functions.
Vrzgula, Andrej, Krajničák, R., Gatěk, Jiří, Dudešek, Bohumil, Kotočová, K., Ponížil, Petr, Kotoč, Július   +6 more
core   +1 more source

Moderating role of performance anxiety, sexual knowledge and sexual attitude on the relationship between severity of sexual dysfunctions and marital problems

مجله علوم روانشناختی, 2016
Marital relationships are influenced by sexual dysfunctions resulting in development and or continuing marital problems. The present study aimed at examining the moderating role of performance anxiety, sexual knowledge and attitudes on the relationship ...
MohammadAli Besharat, Negar Mazloomhoseini, Masoud Gholamali Lavasani, BahramAli Ghanbari Hashemabadi   +3 more
doaj  

Sexual dysfunctions and sexual behaviors of normal weight, overweight and obese sexual minority men

European Psychiatry, 2021
Introduction With the growing recognition of overweightness and obesity as significant, international public health concerns, the body of research investigating the relationship between body mass index (BMI), sexual health and sexual functioning in ...
H. Pereira
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Measuring sexual function in community surveys: development of a conceptual framework. [PDF]

, 2012
Among the many psychometric measures of sexual (dys)function, none is entirely suited to use in community surveys. Faced with the need to include a brief and non-intrusive measure of sexual function in a general population survey, a new measure was ...
Kaye Wellings, Wellings, Kaye, Mitchell, Kirstin R., Kirstin R. Mitchell, Mitchell, Kirstin R   +4 more
core   +1 more source

Breaking the Taboo: Unveiling the Prevalence and Predictors of Female Sexual Dysfunction in Tunisia

European Psychiatry
Introduction Female sexuality is a complex and multifactorial domain that can be influenced by a variety of psychological, biological, relational, and sociocultural factors.
K. Razki, A. Larnaout, C. Najar, S. Ben Aissa, R. Lansari, W. Melki   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source