Results 161 to 170 of about 247,698 (307)

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Beyond the binary: disparities in food consumption and alcohol intake among Brazilian sexual minorities. [PDF]

BMC Nutr
Cruz PGCES, Rocha DDC, Carvalho AM, Teixeira CD, Maciel GG, Lopes MS, Jacob MCM, Gomes SM.   +7 more
europepmc   +1 more source

Do Beliefs About Sexual Orientation Predict Sexual Identity Labeling Among Sexual Minorities? [PDF]

Arch Sex Behav, 2023
Morandini JS, Menzies RE, Moreton SG, Dar-Nimrod I.   +3 more
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Understanding Intimate Partner Violence Among Ethnic and Sexual Minorities: Lived Experiences of Queer Women in Norway. [PDF]

Violence Against Women, 2022
Ummak E, Turken S, Akin D.
europepmc   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

PROTOCOL: Risk and strength factors that predict criminal conduct among under-represented genders and sexual minorities: A systematic review and meta-analysis. [PDF]

Campbell Syst Rev, 2023
Chambers A, Brown S, Peterson-Badali M.
europepmc   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Cardiovascular disease prevention in sexual minorities, A fellow's voice. [PDF]

Am J Prev Cardiol
Punnanithinont N.
europepmc   +1 more source

Examination of Outcomes among Sexual Minorities in Treatment for Obsessive-Compulsive and Related Disorders. [PDF]

J Obsessive Compuls Relat Disord, 2022
Bezahler A, Kuckertz JM, Schreck M, Narine K, Dattolico D, Falkenstein MJ.   +5 more
europepmc   +1 more source