Results 231 to 240 of about 21,005 (271)

Critical role of the CMGC insert sequence for tyrosine autophosphorylation in the protein kinase DYRK1B. [PDF]

Sci Rep
Detro-Dassen S, Schwandt K, Helmich P, Düsterhöft S, Becker W.   +4 more
europepmc   +1 more source

SF3B1^K700E mutant cells exhibit altered transcription and more efficient pause release.

Mahtab Dastpak (11783247), Claudia A. Mimoso (22881385), Moein Farshchian (11783232), Christina L. Paraggio (22881388), Claudia E. Leonard (22881391), Shanye Yin (837503), Binkai Chi (22881394), Kelsey W. Nassar (15088053), R. Grant Rowe (21093611), Jiuchun Zhang (22881397), Zhonggang Hou (256486), George Q. Daley (115819), Karen Adelman (4540336), Robin Reed (310378)   +13 more
openalex   +1 more source

Multipurpose RNA maturation factors dysregulate multiple mRNA processing steps simultaneously and provide new therapeutic opportunities. [PDF]

RNA Biol
Paira S, Borden KLB.
europepmc   +1 more source

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review). [PDF]

Oncol Rep
Zhu W, Wu Z, Luv C, Bao B, Zhao W, Chen G, Yang H, Ai H, Liu F, Li Z.   +9 more
europepmc   +1 more source

SpliceUp: Predicting SF3B1 mutations in individual cells via aberrant splice site activation from scRNA-seq data

Kholmatov M, Prummel KD, Guezguez B, Hellström-Lindberg E, Moura PL, Zaugg JB.   +5 more
europepmc   +1 more source

Proteomic and Phosphoproteomic Characteristics of the Retina, Choroid, and Sclera in Guinea Pigs with Form-Deprivation Myopia. [PDF]

Mol Cell Proteomics
Song Y, Xu Z, Li HT, Xie Y, Zhao L, Feng J, Luo A, Dai J, Li J, Guo X, Song J, Bi H.   +11 more
europepmc   +1 more source

Inflammatory stromal and T cells mediate human bone marrow niche remodeling in clonal hematopoiesis and myelodysplasia. [PDF]

Nat Commun
Prummel KD, Woods K, Kholmatov M, Schmitt EC, Vlachou EP, Labyadh M, Wehner R, Poschmann G, Stühler K, Winter S, Oelschlaegel U, Wobus M, Schwartz LS, Moura PL, Hellström-Lindberg E, Rajalingam K, Theobald M, Trowbridge JJ, Carron C, Jaffredo T, Schmitz M, Platzbecker U, Zaugg JB, Guezguez B.   +23 more
europepmc   +1 more source

The cancer-associated SF3B1^K700E spliceosome mutation confers enhanced sensitivity to BV-6-induced cytotoxicity. [PDF]

Cell Death Dis
Roets LE, Blayney JK, McMillan HP, Preston PJ, Mutch AM, Mills KI, Savage KI, Lappin KM.   +7 more
europepmc   +1 more source

Data from Erythroid Differentiation Enhances RNA Mis-Splicing in <i>SF3B1</i>-Mutant Myelodysplastic Syndromes with Ring Sideroblasts

Pedro Luís Moura, Teresa Mortera‐Blanco, Isabel Juliana Hofman, Gabriele Todisco, Warren W. Kretzschmar, Ann-Charlotte Björklund, Maria Creignou, Michael Hagemann-Jensen, Christoph Ziegenhain, David Cabrerizo Granados, Indira Barbosa, Gunilla Walldin, Monika Jansson, Neil Ashley, Adam J. Mead, Vanessa Lundin, Marios Dimitriou, Tetsuichi Yoshizato, Petter Woll, Seishi Ogawa, Rickard Sandberg, Sten Eirik W. Jacobsen, Eva Hellström‐Lindberg   +22 more
openalex   +1 more source

Significance of Mutation Spots and Concurrent Gene Mutations on Prognosis and Clinical Outcomes in Myelodysplastic Syndromes With SF3B1 Mutation. [PDF]

Cancer Med
Liu Q, Xu F, Guo J, Xu F, Huang X, Chen J, Jin J, Zhou L, He Q, Wu D, Song L, Zhang Z, Guo C, Su J, Zhang Y, Yan M, Chang C, Li X, Wu L.   +18 more
europepmc   +1 more source