Results 51 to 60 of about 32,149 (266)

Microorganisms—An Effective Tool to Intensify the Utilization of Sulforaphane

Foods, 2022
Sulforaphane (SFN) was generated by the hydrolysis of glucoraphanin under the action of myrosinase. However, due to the instability of SFN, the bioavailability of SFN was limited. Meanwhile, the gut flora obtained the ability to synthesize myrosinase and
Xiude Li, Yihan Wang, Guoping Zhao, Guangmin Liu, Pengjie Wang, Jinwang Li   +5 more
doaj   +1 more source

Glucosinolate and Isothiocyanate Profiles in Different Varieties of Raphanus sativus Seed via Multivariate Data Analysis

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Through HPLC–MS/MS analysis and multivariate statistics, raphani semen (RS) varieties with high functional components were screened. The white raphani semen “Xuebawang” was identified as ideal for further study due to its high bioactive content: glucoraphenin (9010.27 mg/100 g), glucoraphanin (1027.76 mg/100 g), sulforaphane (66.14 mg/100 g), and ...
Yonghua Li, Dongmei Lin, Peng Wu, Rui Gao, Jingxiu Bi, Yuying Jiang, Tong Zhao, Xuexia Yuan, Jianhan Xu, Pingxiang Liu, Yutao Wang   +10 more
wiley   +1 more source

Sulforaphane suppresses paraquat-induced oxidative damage in bovine in vitro-matured oocytes through Nrf2 transduction pathway

Ecotoxicology and Environmental Safety, 2023
Sulforaphane (SFN), a bioactive phytocompound extracted from cruciferous plants, has received increasing attention due to its vital cytoprotective role in eliminating oxidative free radical through activation of nuclear factor erythroid 2-related factor (
Zhiqiang Feng, Tengfei Wang, Yawen Sun, Siying Chen, Haisheng Hao, Weihua Du, Huiying Zou, Dawei Yu, Huabin Zhu, Yunwei Pang   +9 more
doaj   +1 more source

Nonlinear generalized minimum variance control under actuator saturation [PDF]

, 2005
A new Generalized Minimum Variance control law has been derived recently for the controlof nonlinear multivariable systems. In this paper we restrict our interest tosingle-input, single-output plants with input nonlinearities in the form of hard ...
Grimble, Michael J., Majecki, Pawel
core   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2

Communications Biology, 2023
Selenoprotein P (SeP) is a major selenoprotein in serum predominantly produced in the liver. Excess SeP impairs insulin secretion from the pancreas and insulin sensitivity in skeletal muscle, thus inhibition of SeP could be a therapeutic strategy for ...
Xinying Ye, Takashi Toyama, Keiko Taguchi, Kotoko Arisawa, Takayuki Kaneko, Ryouhei Tsutsumi, Masayuki Yamamoto, Yoshiro Saito   +7 more
doaj   +1 more source

Biomarkers in small fiber neuropathy

Exploration of Neuroprotective Therapy, 2022
Small fiber neuropathy (SFN) is a relatively common, but largely understudied neurological syndrome which has affected the lives of many globally. The common symptoms of SFN include pain, dysesthesia, and autonomic dysfunction, which are caused by damage
Amanda C. Y. Chan, Kathleen Ong, Jonathan J. Y. Ong, Vijay K. Sharma, Hiu Yi Wong, Joy Vijayan   +5 more
doaj   +1 more source

Speech and Deep Brain Stimulation in Parkinson's Disease, Essential Tremor, and Dystonia: A Systematic Review and Meta‐analysis

Movement Disorders, EarlyView.
Abstract Deep brain stimulation (DBS) effectively treats motor symptoms in movement disorders but often compromises speech through incompletely defined mechanisms. We conducted a PROSPERO‐registered systematic review and meta‐analysis of publications through August 2024 (CRD42024527738).
Elina Tripoliti, Takashi Tsuboi, Michael T. Barbe, Mario Sousa, Julie Barkmeier‐Kraemer, Hannah Jergas, Gaia Arno, Nicole Buie, Mikayla Day, Petr Krýže, Jayson R. Nelson, Aaron E.L. Warren, Shervin Rahimpour, Jan Rusz, Paul Krack, Kristina Simonyan   +15 more
wiley   +1 more source

Investigation of magnesium aluminometasilicate (Neusilin US2) based surface solid dispersion of sorafenib tosylate using QbD approach: In vitro and in vivo pharmacokinetic study

ADMET and DMPK
Background and purpose: Sorafenib tosylate (SFN), a potent multikinase inhibitor, is used for the treatment of various cancers. However, it shows limited therapeutic applications due to its poor biopharmaceutical properties.
Bijoy Kumar Panda, Bothiraja Chellampillai, Sharad Ghodke, Ashwin Mali, Ravindra Kamble   +4 more
doaj   +1 more source

Brain awareness week and beyond: encouraging the next generation. [PDF]

, 2009
The field of neuroscience is generating increased public appetite for information about exciting brain research and discoveries. As stewards of the discipline, together with FUN and others, the Society for Neuroscience (SfN) embraces public outreach and ...
Chang, Eun-Joo, McNerney, Colleen D, Spitzer, Nicholas C   +2 more
core   +1 more source