Results 181 to 190 of about 3,280 (212)

Novel SFTSV Phylogeny Reveals New Reassortment Events and Migration Routes [PDF]

open access: yesVirologica Sinica, 2020
Severe fever with thrombocytopenia syndrome virus (SFTSV), the causative agent of a febrile human disease, was first identified from central and eastern provinces in China, and later in Japan and South Korea. Hubei Province is one of the major SFTS epidemic areas in the central part of China.
Xin Zheng, Hualin Wang, Boyun Liang
exaly   +3 more sources

SFTSV induces liver ferroptosis through m6A-related ferritinophagy

open access: yesAutophagy
Severe fever with thrombocytopenia syndrome (SFTS) is a widely prevalent infectious disease caused by severe fever with thrombocytopenia syndrome virus (SFTSV). SFTSV infection carries a high mortality rate and has emerged to be a public health concern. SFTSV infection could induce many classical cell death pathways. Ferroptosis, a novel iron-dependent
Zhiwei Wu, Bingxin Liu, Na Jiang
exaly   +4 more sources

An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV [PDF]

open access: yesScience China Life Sciences, 2013
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in rural areas of China and is caused by a new bunyavirus, SFTSV, named after the disease. The transmission vectors and animal hosts of SFTSV are unclear. Ticks are the most likely transmission vectors and domestic animals, including goats, dogs, and cattle, are ...
Hongling Wen, Xue-Jie Yu
exaly   +3 more sources

Preparation of a polyclonal antibody against the non-structural protein, NSs of SFTSV

Protein Expression and Purification, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is newly discovered virus which is the member of the order Bunyavirales, family phenuiviridae, phlebovirus genus. Its genome is composed of 3 segments of negative-sense RNA L, M and S. NSs is a non structure protein encoded by S segment which is important for viral replication and virulence. NSs
Yong Gang Li
exaly   +3 more sources

Inhibition of SFTSV replication in humanized mice by a subcutaneously administered anti-PD1 nanobody

open access: yesEMBO Molecular Medicine
Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening disease caused by a novel bunyavirus (SFTSV), mainly transmitted by ticks. With no effective therapies or vaccines available, understanding the disease’s mechanisms is crucial ...
Yuxin Chen, Mengmeng JI, Zhiwei Wu
exaly   +2 more sources

SFTSV NSs Sequesters the Complex of SFTSV NP‐SAFA to Suppress SAFA Mediated Immune Response

Journal of Medical Virology
ABSTRACT Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging pathogenic Bunyavirus with a fatality rate of up to 30%. SFTSV nonstructural protein (NSs) forms viroplasm‐like structures in the cytoplasm of infected cells, sequestering antiviral proteins ...
Xin‐bo Huang   +10 more
openaire   +2 more sources

Virology of SFTSV

2019
At first, the basic structures of the viral genomes of severe fever with thrombocytopenia syndrome virus (SFTSV) and related viruses are shown. Then the structures and functions of structural and nonstructural proteins of SFTSV are discussed. Finally, recent information relating to the basic property of SFTSV, cytopathic effect, plaque formation and ...
openaire   +1 more source

Experimental Infection of Ticks with SFTSV

Many members in the class Bunyaviricetes are tick-borne viruses. Experimental viral infection of ticks is greatly needed to better understand the tick-virus interactions. To date, multiple laboratory techniques for the viral infection of ticks have been documented.
Jiao, Xu, Xue-Jie, Yu
openaire   +2 more sources

Molecular Epidemiology of SFTSV

2019
Indigenous severe fever with thrombocytopenia syndrome (SFTS) has been reported to be endemic to China, South Korea, and Japan. To date, several molecular epidemiology and phylogenetic studies of SFTS virus (SFTSV) have been performed. At the beginning of this review, the impact of the source of the samples (i.e., patient specimens vs.
openaire   +1 more source

Current Progress of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Vaccine Development

open access: yesViruses
SFTSV is an emerging tick-borne virus causing hemorrhagic fever with a case fatality rate (CFR) that can reach up to 27%. With endemic infection in East Asia and the recent spread of the vector tick to more than 20 states in the United States, the SFTSV ...
Jae U. Jung, Dokyun Kim, Chih-Jen Lai
exaly   +2 more sources

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