Results 191 to 200 of about 54,917 (299)

Characterization of AF Recurrence and Substrate Health by Electrographic Flow (EGF) Consistency in EGF Mapping

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Electrographic flow (EGF) mapping is an FDA 510(k)‐cleared method for visualizing atrial activation wavefronts in atrial fibrillation (AF). Its clinical efficacy in detecting AF sources was demonstrated in the FLOW‐AF randomized controlled trial, and the underlying machine learning strategy used to develop and refine EGF source ...
Steven Castellano, Marloes Jansen, Lucas V. A. Boersma, Marisa van der Graaf, Melissa H. Kong, Kostiantyn Ahapov, Philip Haeusser, Moritoshi Funasako, John D. Hummel, Wilber W. Su   +9 more
wiley   +1 more source

Design principles for natural SGLT2 modulators from multi-scale computation. [PDF]

R Soc Open Sci
Khibech O, Abadi S, Bouhrim M, Hammouti Y, Merzouki M, Addi M, Al-Zharani M, Nasr FA, Qurtam AA, Challioui A.   +9 more
europepmc   +1 more source

Temporal Association Between Intrathoracic Impedance and Tachyarrhythmia Occurrence

Journal of Cardiovascular Electrophysiology, EarlyView.
A decrease in intrathoracic impedance is temporally associated with subsequent AF occurrence and, at the episode level, with a shorter time to VT. These findings suggest that daily intrathoracic impedance may provide information on short‐term changes preceding tachyarrhythmia occurrence.
Monika Butkuvienė, Andrius Petrėnas, Andrius Sološenko, Anneli Olsson, Rasmus Borgquist, Pyotr G. Platonov   +5 more
wiley   +1 more source

Early Relative eGFR Decline After SGLT2 Inhibitor Initiation in Heart Failure: Clinical Correlates and Pretreatment-Anchored 12-Month Trajectories. [PDF]

J Clin Med
Suzuki Y, Onishi T, Nakano Y, Shimoda M, Goto R, Suzuki T, Amano T.   +6 more
europepmc   +1 more source

SGLT2 inhibition: a new era in renoprotective medicine?

The Lancet Diabetes & Endocrinology, 2017
Muskiet, Marcel H.A., Heerspink, Hiddo J.L., van Raalte, Daniël H.   +2 more
openaire   +3 more sources

Type 1 diabetes in the era of obesity: Pathophysiology and therapeutic implications

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Type 1 diabetes is defined by immune‐mediated beta‐cell failure and dependence on exogenous insulin. That definition is correct, but it may not fully describe many people seen in current clinical practice. Overweight and obesity are now common in type 1 diabetes, leading to variable combinations of high insulin requirement, hypertension ...
Zachary Bloomgarden
wiley   +1 more source

SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice

Circulation Research
Justin H. Berger, Timothy R. Matsuura, Caitlyn E. Bowman, Renee Taing, Jiten Patel, Ling Lai, Teresa C. Leone, Jeffrey D. Reagan, Saptarsi M. Haldar, Zoltan Arany, Daniel P. Kelly   +10 more
openaire   +2 more sources

Renal glycogen handling in diabetes: A narrative review of diabetic kidney disease pathogenesis

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Kidney disease is a major microvascular complication of diabetes, affecting approximately 40% of individuals with diabetes, and is a leading cause of end‐stage renal disease. Besides the functional consequences of hyperglycemia; hemodynamic alterations are well understood.
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan Chandrahasa Shetty, Sujina Simon Sailet   +3 more
wiley   +1 more source

Recurrent Euglycemic Diabetic Ketoacidosis Weeks After SGLT2 Inhibitor Cessation: A Case Report. [PDF]

Case Rep Endocrinol
Mansour C, Katrib E, Mansour M, Fares M.
europepmc   +1 more source

Clinical characteristics and disease progression of typical adult‐onset type 1 diabetes and insulin‐dependent latent autoimmune diabetes in adults

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims We investigated the characteristics of typical adult‐onset type 1 diabetes (T1D) and insulin‐dependent latent autoimmune diabetes in adults (LADA) in Thailand. Methods This retrospective chart review enrolled typical T1D and insulin‐dependent LADA patients diagnosed at age ≥30 years, and who were followed up at Siriraj Hospital, Thailand,
Chanoknan Luksameejaroenchai, Thanida Tangjarusritaratorn, Lukana Preechasuk   +2 more
wiley   +1 more source