Results 211 to 220 of about 54,917 (299)

Parasympathetic dysfunction assessed by deep‐breathing CVR‐R is associated with early discontinuation of oral semaglutide in type 2 diabetes: A multicenter retrospective study

Journal of Diabetes Investigation, EarlyView.
Lower CVR‐R during deep breathing (CVR‐R_DB), a marker of parasympathetic function, was associated with early discontinuation of oral semaglutide due to nausea and/or vomiting in patients with type 2 diabetes. CVR‐R_DB may support risk stratification at treatment initiation.
Kazuma Ogiso, Takahisa Deguchi, Shigeru Kawade, Aiko Arimura, Yoshihiko Nishio, Katsutaro Morino   +5 more
wiley   +1 more source

Real‐world effectiveness and safety of enavogliflozin in patients with type 2 diabetes: A 24‐week prospective multicenter observational study in Korea

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction To evaluate the real‐world effectiveness and safety of enavogliflozin as a single‐pill formulation (Enavo group; enavogliflozin 0.3 mg) or fixed‐dose combination with metformin (EnavoMet group; enavogliflozin 0.3 mg/metformin 1000 mg) in patients with type 2 diabetes (T2DM) in Korean primary care.
Hyunji Sang, Yeongtaek Hwang, Selin Woo, Soo Jin Yun, Meehoh Kim, Ho Geol Woo, Joo Young Kim, Dong Keon Yon, Sang Youl Rhee   +8 more
wiley   +1 more source

The Influence of SGLT2 Inhibitors on the Immune System and Inflammatory Processes in Kidney Transplantation. [PDF]

Int J Mol Sci
García-Sánchez A, Ortíz-Lazareno P, Pazarín-Villaseñor L, Díaz-de la Cruz EN, Mora-Jiménez A, Andrade-Sierra J, Cardona-Muñoz EG, Totsuka-Sutto SE, Gómez-Hermosillo LF, Casillas-Moreno J, Campos-Bayardo TI, Román-Rojas D, Garzón-Lamarque JA, Miranda-Díaz AG.   +13 more
europepmc   +1 more source

The low fasting serum C‐peptide level was associated with reduced sural nerve action potential amplitudes: A cross‐sectional study of Japanese type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
Low fasting serum C‐peptide levels were independently associated with abnormal sural nerve action potential amplitude measured by DPNCheck® in patients with type 2 diabetes. Fasting serum C‐peptide may serve as a clinically relevant marker for diabetic polyneuropathy. ABSTRACT Aims/Introduction The association between the fasting serum C‐peptide levels
Taichi Muramatsu, Kaori Inoue‐Yamamoto, Daisuke Yamamuro, Akifumi Kushiyama   +3 more
wiley   +1 more source

Short-term effects of an SGLT2 inhibitor on divalent ions in autosomal dominant polycystic kidney disease: a randomized crossover trial. [PDF]

Clin Kidney J
Roth L, Harmacek D, Schachtner T, George B, Hofmann C, Georgalis AD, Venzin RM, Hofmann P, Fehr TH.   +8 more
europepmc   +1 more source

Changes in liver steatosis and liver stiffness following Empagliflozin treatment in patients with MASLD and type 2 diabetes: A single‐arm pre–post study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) is common in subjects with type 2 diabetes mellitus (T2DM), being linked to a higher risk for the development of liver‐related and cardiovascular diseases.
Mobina Shieh, Davood Dalil, Alireza Arefzadeh, Maryam Shiehmorteza   +3 more
wiley   +1 more source

MAP17 Orchestrates SGLT2-Dependent Glycolytic Reprogramming to Drive Trained Immunity and Accelerate Atherosclerosis. [PDF]

Arterioscler Thromb Vasc Biol
Wu J, Wang L, Zou F, Liu F, Fang G, Cheng K, Gao H, Zhi K, Qu L.   +8 more
europepmc   +1 more source

Increased incidence and healthcare burden of bullous pemphigoid: A population‐based cohort study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Bullous pemphigoid prevalence in Germany has risen substantially, particularly among older adults, and is associated with increased comorbidity burden, threefold higher mortality and markedly greater healthcare utilization and costs. These findings highlight a growing clinical and economic burden in ageing populations requiring improved management ...
Anna C. Meyer, Inka Albrecht, Lena Hasemann, Jana Diekmannshemke, Oliver Damm, Daniel Gensorowsky, Julian Witte, Sven R. Quist, Ulrike Raap, Enno Schmidt   +9 more
wiley   +1 more source

Dapagliflozin Beyond Glucose Lowering: Mechanisms of Renal and Systemic Protection. [PDF]

Pathophysiology
Wise ML, Alli AA.
europepmc   +1 more source

High urine osmolality and elevated urine sodium predict early nonresponse to fluid restriction in patients with the syndrome of inappropriate antidiuresis

Journal of Internal Medicine, EarlyView.
Abstract Introduction Fluid restriction is the current first‐line therapy for hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD), yet up to 50% of patients do not achieve an adequate plasma sodium correction. Reported predictors of nonresponse include urine osmolality >500 mOsm/kg, the Furst ratio >1 [(UNa + UK)/(PNa)], urine ...
Michelle Patricia Müller, Laura Potasso, Ewout J. Hoorn, Julie Refardt, Mirjam Christ‐Crain, for the HIT study investigators   +5 more
wiley   +1 more source