Results 41 to 50 of about 25,234 (166)

Severe intoxication caused by sodium-glucose cotransporter 2 inhibitor overdose: a case report

BMC Pharmacology and Toxicology, 2020
Background Sodium-glucose cotransporter 2 (SGLT2) inhibitors inhibit SGLT2, which is expressed in the proximal renal tubule, and thus reduce blood glucose levels by enabling the urinary excretion of excess glucose.
Miho Nakamura, Junya Nakade, Tadashi Toyama, Masaki Okajima, Takumi Taniguchi   +4 more
doaj   +1 more source

SGLT2 inhibitors: expanding their Empire beyond diabetes [PDF]

The Lancet Diabetes & Endocrinology, 2021
Muskiet, Marcel H. A., Heerspink, Hiddo J. L., van Raalte, Daniël H.   +2 more
openaire   +3 more sources

SGLT2 inhibitors: Beyond glycemic control

Journal of Clinical & Translational Endocrinology
Multiple randomized controlled trials have extensively examined the therapeutic effectiveness of sodium-glucose cotransporter 2 (SGLT2) inhibitors, ushering in a transformative approach to treating individuals with type 2 diabetes mellitus (DM). Notably, emerging reports have drawn attention to the potential positive impacts of SGLT2 inhibitors in ...
Irtiza Hasan, Tasnuva Rashid, Vishal Jaikaransingh, Charles Heilig, Emaad M. Abdel-Rahman, Alaa S. Awad   +5 more
openaire   +3 more sources

Trends in Healthcare Costs in Heart Failure and Its Clinical Phenotypes During the Implementation of SGLT2 Inhibitors: A Finnish Registry Study

ClinicoEconomics and Outcomes Research
Johan Liseth Hansen,1,2 Miikka Tarkia,3 Marija Vasilevska,1 Patrik Sandin,1 Eralda Asllanaj,4 Karlijn Wammes,4 Johan Mesterton,1,5 KE Juhani Airaksinen6 1Quantify Research, Stockholm, Sweden; 2Department of Health Management and Health Economics ...
Hansen JL, Tarkia M, Vasilevska M, Sandin P, Asllanaj E, Wammes K, Mesterton J, Airaksinen KEJ   +7 more
doaj  

Impact of Sodium–Glucose Cotransporter 2 Inhibitors on Acute Kidney Injury Post Off-Pump Coronary Artery Bypass Grafting: A Retrospective Cohort Study and Meta-Analysis

Reviews in Cardiovascular Medicine
Background: Sodium–glucose cotransporter 2 (SGLT2) inhibitors, a novel class of oral antihyperglycemic medications prescribed for type 2 diabetes mellitus, play a beneficial role in slowing the progression of heart failure.
Xiaozheng Zhou, Yilin Pan, Kun Hua, Xiubin Yang   +3 more
doaj   +1 more source

Unmasking of normocalcemic primary hyperparathyroidism after sodium-glucose cotransporter-2 inhibitor initiation

European Journal of Case Reports in Internal Medicine
Sodium-glucose cotransporter-2 (SGLT2) inhibitors have complex interactions with bone metabolism, including an increase in parathyroid hormone (PTH) levels.
Christodoulos Dolapsakis, Emmanouil Karofylakis, Stamatios Chalvatzis   +2 more
doaj   +1 more source

SGLT2 Inhibitors for Cardioprotection

Oman Medical Journal, 2023
Sulthan Al Rashid, P. Elango, Syed Ziaur Rahman   +2 more
openaire   +3 more sources

SGLT2 Inhibitors in MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) Associated with Sustained Hepatic Benefits, Besides the Cardiometabolic

Pharmaceuticals
Background and Aims: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have shown promise in metabolic dysfunction-associated steatotic liver disease (MASLD). This large real-world study aimed to evaluate the effects of SGLT2 inhibitors on MASLD patients’
Mohamad Suki, Ashraf Imam, Johnny Amer, Yael Milgrom, Muhammad Massarwa, Wadi Hazou, Yariv Tiram, Ofer Perzon, Yousra Sharif, Joseph Sackran, Revital Alon, Nachum Lourie, Anat Hershko Klement, Safa Shibli, Tamer Safadi, Itamar Raz, Abed Khalaileh, Rifaat Safadi   +17 more
doaj   +1 more source

SGLT2 inhibitor use and renal outcomes in low-risk population with diabetes mellitus and normal or low body mass index

BMJ Open Diabetes Research & Care
Introduction Recent post hoc analyses indicate that patients with normal or low body mass index (BMI) benefit from sodium-glucose cotransporter-2 (SGLT2) inhibitor use. We aimed to evaluate the effects of SGLT2 inhibitors on renal and patient outcomes in
Hye Ryoun Jang, Jung Eun Lee, Wooseong Huh, Yun Soo Lee, Goeun Park, Kyungho Lee, Junseok Jeon   +6 more
doaj   +1 more source

Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors from Natural Products: Discovery of Next-Generation Antihyperglycemic Agents

Molecules, 2016
Diabetes mellitus is a chronic condition associated with the metabolic impairment of insulin actions, leading to the development of life-threatening complications. Although many kinds of oral antihyperglycemic agents with different therapeutic mechanisms
Chang-Ik Choi
doaj   +1 more source