Results 11 to 20 of about 46,872 (214)

Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Water and Sodium Metabolism

Frontiers in Pharmacology, 2022
Sodium-glucose cotransporter 2 (SGLT2) inhibitors exert hypoglycemic and diuretic effects by inhibiting the absorption of sodium and glucose from the proximal tubule.
Jun Tang, Jun Tang, Lifang Ye, Lifang Ye, Qiqi Yan, Qiqi Yan, Xin Zhang, Xin Zhang, Lihong Wang, Lihong Wang   +9 more
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Electrocardiographic changes associated with SGLT2 inhibitors and non-SGLT2 inhibitors: A multi-center retrospective study

Frontiers in Cardiovascular Medicine, 2022
BackgroundSodium-glucose co-transporter 2 (SGLT2) inhibitors has been shown with cardiovascular benefit in type 2 diabetes mellitus (T2DM) patients. However, its osmotic diuresis still concern physicians who may look for possible electrolyte imbalance ...
Victor Chien-Chia Wu, Kai-Pin Chiu, Chun-Li Wang, Chiu-Yi Hsu, Hui-Tzu Tu, Yu-Tung Huang, Chih-Hsiang Chang, Chien-Hao Huang, Chang-Fu Kuo, Chang-Fu Kuo, Shao-Wei Chen, Shao-Wei Chen, Pao-Hsien Chu, Shang-Hung Chang, Shang-Hung Chang, Shang-Hung Chang   +15 more
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Pleiotropic effect of sodium-glucose cotransporter 2 inhibitors on blood pressure

Frontiers in Cardiovascular Medicine, 2022
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been incorporated as guideline-directed medical therapy for heart failure with reduced ejection fraction.
Ting-Wei Kao, Ting-Wei Kao, Chin-Chou Huang, Chin-Chou Huang, Chin-Chou Huang, Chin-Chou Huang   +5 more
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Benefits of SGLT2 inhibitors in arrhythmias

Frontiers in Cardiovascular Medicine, 2022
Some studies have shown that sodium-glucose cotransporter (SGLT) 2 inhibitors can definitively attenuate the occurrence of cardiovascular diseases such as heart failure (HF), dilated cardiomyopathy (DCM), and myocardial infarction.
Jinghan Gao, Genlong Xue, Ge Zhan, Xinying Wang, Jiatian Li, Xiaolei Yang, Yunlong Xia   +6 more
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Risk of diabetic ketoacidosis of SGLT2 inhibitors in patients with type 2 diabetes: a systematic review and network meta-analysis of randomized controlled trials

Frontiers in Pharmacology, 2023
Background: Sodium–glucose cotransporter-2 (SGLT2) inhibitors have proven to be effective in improving glycemic control in patients with type 2 diabetes mellitus (T2DM). However, the risk of diabetic ketoacidosis (DKA) in patients remains unclear.
Shiwen Yang, Ying Liu, Shengzhao Zhang, Fengbo Wu, Dan Liu, Qingfang Wu, Hanrui Zheng, Ping Fan, Na Su, Na Su   +9 more
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The association between SGLT2 inhibitors and new-onset arrhythmias: a nationwide population-based longitudinal cohort study

Cardiovascular Diabetology, 2020
Background Clinical trials have shown the cardiovascular protective effect of sodium–glucose cotransporter-2 (SGLT2) inhibitors and reduced hospitalization for heart failure. However, no study has investigated the association between SGLT2 inhibitors and
Hung-Yi Chen, Jing-Yang Huang, Wun-Zhih Siao, Gwo-Ping Jong   +3 more
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SGLT2 Inhibitors Play a Salutary Role in Heart Failure via Modulation of the Mitochondrial Function

Frontiers in Cardiovascular Medicine, 2020
Three cardiovascular outcome trials of sodium glucose cotransporter 2 (SGLT2) inhibitors, including the EMPA-REG OUTCOME trial, CANVAS Program, and DECLARE TIMI 58 trial, revealed that SGLT2 inhibitors were superior to a matching placebo in reducing ...
Yasuhiro Maejima
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Renoprotective effect of chronic treatment with sodium-glucose cotransporter 2 inhibitors and its associated factors in Japanese patients with chronic heart failure and diabetes

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Recent clinical trials have shown that sodium-glucose cotransporter 2 (SGLT2) inhibitors have beneficial effects on renal function in heart failure patients. This study confirmed the renoprotective effect of treatment with SGLT2 inhibitors in
Go Yokouchi, Takeshi Horio, Naoki Matsumoto, Kohei Fukuda, Ryutaro Yoshimura, Ryosuke Fujiwara, Yujiro Matsuoka, Yuya Sakamoto, Yoshio Iwashima, Yoshiyuki Oshiro, Kohei Fujimoto, Noriaki Kasayuki   +11 more
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Favorable pleiotropic effects of sodium glucose cotransporter 2 inhibitors: head-to-head comparisons with dipeptidyl peptidase-4 inhibitors in type 2 diabetes patients

Cardiovascular Diabetology, 2020
Background Sodium glucose cotransporter 2 (SGLT2) inhibitors have shown greater reductions of cardiovascular event risks than dipeptidyl peptidase-4 (DPP4) inhibitors, whereby possible mechanisms may involve the better pleiotropic effects of SGLT2 ...
Shih-Chieh Shao, Kai-Cheng Chang, Swu-Jane Lin, Rong-Nan Chien, Ming-Jui Hung, Yuk-Ying Chan, Yea-Huei Kao Yang, Edward Chia-Cheng Lai   +7 more
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The Incidence and Risk Factors of Urinary Tract Infection in Patients with Type 2 Diabetes Mellitus Using SGLT2 Inhibitors: A Real-World Observational Study

Medicines, 2022
Background: The incidence and risk of urinary tract infection (UTI) in patients with type 2 diabetes mellitus (T2DM) who use sodium glucose co-transporter-2 (SGLT2) inhibitors are still controversial.
Suriyon Uitrakul, Krittika Aksonnam, Pimchanok Srivichai, Sorawit Wicheannarat, Supatcha Incomenoy   +4 more
doaj   +1 more source