Results 1 to 10 of about 34,392 (132)

Superior esterolytic activity in environmental Lactococcus lactis strains is linked to the presence of the SGNH hydrolase family of esterases [PDF]

JDS Communications, 2020
Lactococcus lactis strains are widely used in the dairy industry in fermentation processes for production of cheese and fermented milks. However, the esterolytic activity of L. lactis is not generally considered high.
Desirée Román Naranjo, Michael Callanan, Anne Thierry, Olivia McAuliffe   +3 more
doaj   +7 more sources

P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation. [PDF]

PLoS Pathogens, 2014
The O-acetylation of polysaccharides is a common modification used by pathogenic organisms to protect against external forces. Pseudomonas aeruginosa secretes the anionic, O-acetylated exopolysaccharide alginate during chronic infection in the lungs of ...
Perrin Baker, Tyler Ricer, Patrick J Moynihan, Elena N Kitova, Marthe T C Walvoort, Dustin J Little, John C Whitney, Karen Dawson, Joel T Weadge, Howard Robinson, Dennis E Ohman, Jeroen D C Codée, John S Klassen, Anthony J Clarke, P Lynne Howell   +14 more
doaj   +12 more sources

The Active Site of the SGNH Hydrolase-Like Fold Proteins: Nucleophile–Oxyanion (Nuc-Oxy) and Acid–Base Zones [PDF]

Current Research in Structural Biology, 2023
SGNH hydrolase-like fold proteins are serine proteases with the default Asp-His-Ser catalytic triad. Here, we show that these proteins share two unique conserved structural organizations around the active site: (1) the Nuc-Oxy Zone around the catalytic ...
Konstantin Denessiouk, Mark S. Johnson, Vladimir Uversky   +2 more
exaly   +6 more sources

Disordered N-Termini Enhance the Thermostability of SGNH-Hydrolase Family Polyesterases [PDF]

Protein Science
Abstract Polyesters are widely used plastics that persist in the environment due to their resistance to degradation. Microbial polyesterases potentially offer recycling and remediation solutions. However, most polyesterases lack the thermostability and catalytic efficiency required for practical application.
Alessandro T. Caputo, Colin Scott, Lygie Esquirol   +2 more
exaly   +6 more sources

Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans

Molecules, 2022
Acetylated glucuronoxylan is one of the most common types of hemicellulose in nature. The structure is formed by a β-(1→4)-linked D-xylopyranosyl (Xylp) backbone that can be substituted with an acetyl group at O-2 and O-3 positions, and α-(1→2)-linked 4 ...
Leena Penttinen, Vera Kouhi, Régis Fauré, Tatiana Skarina, Peter Stogios, Emma Master, Edita Jurak   +6 more
doaj   +1 more source

Non-targeted metabonomics and transcriptomics revealed the mechanism of mulberry branch extracts promoting the growth of Sanghuangporus vaninii mycelium

Frontiers in Microbiology, 2022
Sanghuangprous vaninii is a wood-inhabiting fungus, and its mycelium and fruiting body show excellent medicinal values. Mulberry is one of the major hosts of S. vaninii, however, the mechanism of mulberry affecting the growth of S.
Jinxi Huo, Yuqing Sun, Meiliang Pan, Huanyan Ma, Tianbao Lin, Zhiqiang Lv, Yougui Li, Shi Zhong   +7 more
doaj   +1 more source

Understanding the structure and function of GDSL-type esterase/lipase genes in pigeon pea for their role under moisture stress conditions

Plant Stress, 2023
The SGNH hydrolase superfamily's GDSL-type esterase/lipase proteins (GELPs) play a crucial role in plant growth and stress tolerance. However, limited knowledge exists regarding the molecular role of GELP genes under drought conditions, especially in ...
Suman Pahal, Kumari Arpita, Harsha Srivastava, Sandhya Sharma, Sapna Grewal, Kishor Gaikwad   +5 more
doaj   +1 more source

Characterization and genomic analysis of a novel lytic phage vB_PstM_ZRG1 infecting Stutzerimonas stutzeri, representing a new viral genus, Elithevirus

Virus Research, 2023
Stutzerimonas stutzeri is an opportunistic pathogen widely distributed in the environment and displays diverse metabolic capabilities. In this study, a novel lytic S.
Ying Chen, Ruizhe Guo, Yantao Liang, Lin Luo, Ying Han, Hongmin Wang, Hong Zhang, Yundan Liu, Kaiyang Zheng, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew McMinn, Min Wang   +14 more
doaj   +1 more source

Metal Ions and Chemical Modification Reagents Inhibit the Enzymatic Activity of Lecithin-Dependent Hemolysin from Vibrio parahaemolyticus

Toxins, 2022
Lecithin-dependent thermolabile hemolysin (LDH) is a virulence factor excreted by Vibrio parahaemolyticus, a marine bacterium that causes important losses in shrimp farming.
Francisco Javier Vazquez-Armenta, Uriel Felipe Valdez-Olmos, Aldo Alejandro Arvizu-Flores, Jesus Fernando Ayala-Zavala, Adrian Ochoa-Leyva, Alonso Alexis Lopez-Zavala   +5 more
doaj   +1 more source

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA). [PDF]

PLoS Pathogens, 2017
The O-acetylation of the essential cell wall polymer peptidoglycan occurs in most Gram-positive bacterial pathogens, including species of Staphylococcus, Streptococcus and Enterococcus. This modification to peptidoglycan protects these pathogens from the
David Sychantha, Carys S Jones, Dustin J Little, Patrick J Moynihan, Howard Robinson, Nicola F Galley, David I Roper, Christopher G Dowson, P Lynne Howell, Anthony J Clarke   +9 more
doaj   +1 more source