Results 11 to 20 of about 522 (119)

The SGNH hydrolase family: a template for carbohydrate diversity. [PDF]

Glycobiology, 2022
Abstract The substitution and de-substitution of carbohydrate materials are important steps in the biosynthesis and/or breakdown of a wide variety of biologically important polymers. The SGNH hydrolase superfamily is a group of related and well-studied proteins with a highly conserved catalytic fold and mechanism composed of 16 member ...
Anderson AC, Stangherlin S, Pimentel KN, Weadge JT, Clarke AJ.   +4 more
europepmc   +3 more sources

Disordered N-termini enhance the thermostability of SGNH-hydrolase family polyesterases. [PDF]

Protein Sci
Abstract Polyesters are widely used plastics that persist in the environment due to their resistance to degradation. Microbial polyesterases potentially offer recycling and remediation solutions. However, most polyesterases lack the thermostability and catalytic efficiency required for practical application.
Ahmed FH, Esquirol L, Royan S, Birgan MM, French NG, Newton S, Caputo AT, Scott C.   +7 more
europepmc   +2 more sources

Crystallization and preliminary X-ray analysis of a highly stable novel SGNH hydrolase (Est24) from Sinorhizobium meliloti. [PDF]

Acta Crystallogr F Struct Biol Commun, 2014
The SGNH hydrolase family includes enzymes that catalyze the hydrolysis of a broad range of substrates. Here, the crystallization and preliminary X-ray crystallographic studies of a novel SGNH hydrolase (Est24) from Sinorhizobium meliloti were performed.
Ryu BH, Nguyen DD, Ngo TD, Oh C, Pandian R, Kim KK, Kim TD.   +6 more
europepmc   +4 more sources

A multicopy Y-chromosomal SGNH hydrolase gene expressed in the testis of the platyfish has been captured and mobilized by a Helitron transposon. [PDF]

BMC Genet, 2014
AbstractBackgroundTeleost fish present a high diversity of sex determination systems, with possible frequent evolutionary turnover of sex chromosomes and sex-determining genes. In order to identify genes involved in male sex determination and differentiation in the platyfishXiphophorus maculatus, bacterial artificial chromosome contigs from the sex ...
Tomaszkiewicz M, Chalopin D, Schartl M, Galiana D, Volff JN.   +4 more
europepmc   +7 more sources

Uncharacterized DUF1574 leptospira proteins are SGNH hydrolases [PDF]

Cell Cycle, 2008
Leptospira borgpetersenii and Leptospira interrogans are nonsporulating bacteria responsible for leptospirosis, which is presumed to be the most widespread zoonosis in the world. This water-borne pathogen is usually transmitted to humans through the contact with contaminated soil or water, via infected animal tissue or rat bites. Consequently, farmers,
Lukasz, Knizewski, Kamil, Steczkiewicz, Krzysztof, Kuchta, Lucjan, Wyrwicz, Dariusz, Plewczynski, Andrzej, Kolinski, Leszek, Rychlewski, Krzysztof, Ginalski   +7 more
openaire   +2 more sources

Characterization and genomic analysis of a novel lytic phage vB_PstM_ZRG1 infecting Stutzerimonas stutzeri, representing a new viral genus, Elithevirus

Virus Research, 2023
Stutzerimonas stutzeri is an opportunistic pathogen widely distributed in the environment and displays diverse metabolic capabilities. In this study, a novel lytic S.
Ying Chen, Ruizhe Guo, Yantao Liang, Lin Luo, Ying Han, Hongmin Wang, Hong Zhang, Yundan Liu, Kaiyang Zheng, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew McMinn, Min Wang   +14 more
doaj   +1 more source

Biochemical Characterization of Multimodular Xylanolytic Carbohydrate Esterases from the Marine Bacterium Flavimarina sp. Hel_I_48. [PDF]

Chembiochem
Multimodular carbohydrate‐active enzymes often combine different catalytic activities for efficient polysaccharide degradation. In this work, the structural and functional characterization of three multimodular xylan‐targeting esterases, Fl6, Fll1 and Fll4 from Flavimarina sp. Hel_I_48, are presented.
Teune M, Döhler T, Bartosik D, Schweder T, Bornscheuer UT.   +4 more
europepmc   +2 more sources

Metal Ions and Chemical Modification Reagents Inhibit the Enzymatic Activity of Lecithin-Dependent Hemolysin from Vibrio parahaemolyticus

Toxins, 2022
Lecithin-dependent thermolabile hemolysin (LDH) is a virulence factor excreted by Vibrio parahaemolyticus, a marine bacterium that causes important losses in shrimp farming.
Francisco Javier Vazquez-Armenta, Uriel Felipe Valdez-Olmos, Aldo Alejandro Arvizu-Flores, Jesus Fernando Ayala-Zavala, Adrian Ochoa-Leyva, Alonso Alexis Lopez-Zavala   +5 more
doaj   +1 more source

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA). [PDF]

PLoS Pathogens, 2017
The O-acetylation of the essential cell wall polymer peptidoglycan occurs in most Gram-positive bacterial pathogens, including species of Staphylococcus, Streptococcus and Enterococcus. This modification to peptidoglycan protects these pathogens from the
David Sychantha, Carys S Jones, Dustin J Little, Patrick J Moynihan, Howard Robinson, Nicola F Galley, David I Roper, Christopher G Dowson, P Lynne Howell, Anthony J Clarke   +9 more
doaj   +1 more source

Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia

Journal of Extracellular Vesicles, Volume 12, Issue 12, December 2023., 2023
Abstract Periodontitis is a chronic inflammatory disease caused by periodontal pathogens in subgingival plaque and is associated with systemic inflammatory diseases. Extracellular vesicles (EVs) released from host cells and pathogens carry a variety of biological molecules and are of interest for their role in disease progression and as diagnostic ...
Younggap Lim, Hyun Young Kim, Dohyun Han, Bong‐Kyu Choi   +3 more
wiley   +1 more source