Results 51 to 60 of about 14,623 (197)

Serendipitous Symptom Control: Allopurinol for Spasticity in a Case of SPG4‐Linked Hereditary Spastic Paraplegia—A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Graphical representation of spasticity and medication changes. (A) Temporal course of lower limb spasticity measured by MAS scores. Following initiation of allopurinol 300 mg daily at baseline (red dashed line), there was a rapid and sustained improvement in spasticity from severe (MAS = 4) to mild (MAS = 1.8) over 12 months of follow‐up, represented ...
Ziad W. Elmezayen, Hossam Salameh, Asem Afana, Anwar Zahran   +3 more
wiley   +1 more source

JUS BELIMBING MANIS (Averrhoa carambola L.) SEBAGAI HEPATOPROTEKTOR PADATIKUS PUTIH (Rattus novergicus strain wistar) YANG DIINDUKSI ANTITUBERKULOSIS RIFAMPISIN DAN ISONIAZID

Saintika Medika, 2018
Latar Belakang: Rifampisin dan isoniazid merupakan obat yang direkomendasikan dalam pengobatan Tuberkulosis yang memiliki efek samping hepatotoksisitas.
Antia Devi Iralawati, Diah Hermayanti, Fathiyah Syafitri   +2 more
doaj   +1 more source

Glycogen Storage Disease in Twins: When Two Lives Reflect One Silent Battle

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Early recognition of hepatomegaly, hypoglycemia, and elevated liver enzymes in infants is crucial for diagnosing glycogen storage disease. Liver biopsy with PAS–diastase staining provides definitive confirmation. Prompt metabolic management and regular follow‐up are essential to prevent progression of fibrosis and long‐term hepatic ...
Rajat Kumar Shah, Sajjad Ahmed Khan, Dikshya Devkota, Manjisha Aryal, Nishan Subedi, Basna Aryal, Binita Gurubacharya, Shamin Parajuli, Ashwini Gupta, Surya Bahadur Parajuli, Huma Kausar   +10 more
wiley   +1 more source

The Effect Of Cigarette And Waterpipe Smoke On Serum Level Of Alanine Aminotransferase And Aspartate Aminotransferase In Male Rats

پیاورد سلامت, 2014
Background and Aim: Smoking can influence liver or heart enzymes. The main aim of this study is to determine the effects of cigarette or waterpipe smoke on serum level of alanine aminotransferase (SGOT) or aspartate aminotransferase (SGPT) in male rats.  
Rahim Ahmadi, Sahar Eshghjoo
doaj   +2 more sources

Effectiveness of Saroglitazar in MASLD Patients: A Prospective, Real‐World Assessment of Liver and Metabolic Health

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Saroglitazar 4 mg daily for 6 months significantly improved liver stiffness, steatosis, and metabolic parameters in patients with MASLD in this prospective, real‐world study. The drug demonstrated meaningful regression of fibrosis and steatosis with stable BMI, highlighting its dual hepatic and metabolic benefits in MASLD management.
Mukulesh Gupta, Harshita Lachhwani, Kumar Praful Chandra, Rajiv Awasthi, Dinesh Kumar   +4 more
wiley   +1 more source

Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Withania somnifera (WS) or Ashwagandha is valued for its anti‐inflammatory, antioxidant, adaptogenic, and memory‐enhancing properties. This randomized, placebo‐controlled and double‐blind study assessed the safety of standardized WS root extract in healthy adult participants over 180 days. The study concluded that WS root extract (200 mg capsules twice
Narendra Vaidya, Ramshyam Agarwal, Pankaj Kshirsagar, Gayatri Ganu, Dheeraj Nagore, Anirudh Mehta, Ashit Vora, Sujit Nair   +7 more
wiley   +1 more source

CORRELATION BETWEEN SGOT AND SGPT LEVELS WITH POSITIVE HBsAg LEVELS

Journal of Vocational Health Studies
Background: Serum Glutamic Oxaloacetate Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) are transaminase enzymes used to determine liver damage. The increase in both enzymes can indicate the level of liver cell damage.
Nisa'ur Rosyidah, Erlinda Widyastuti, Annisa Auliya Rahman, Nur Septia Handayani, Belgis   +4 more
doaj   +1 more source

Pengaruh Suplementasi Madu Trigona Terhadap Parameter Fungsi Hati Dan Ginjal Tikus Albino (Rattus Norvegicus) Yang Diberikan Simvastatin: Effect of Trigona Honey Supplementation on Liver and Kidney Function in SimvastatinAdministered Albino Rats (Rattus Norvegicus) [PDF]

, 2018
Simvastatin is a drug acting on 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase enzyme leading to decrease of lipid level in plasma.
Aliyah, A. (Aliyah), Aminullah, A. (Aminullah), Hidayat, K. (Khaldun), Mamada, S. S. (Sukamto), Rahayu, A. I. (Ayu), Salampe, M. (Mirnawati), Usmar, U. (Usmar)   +6 more
core  

PERBANDINGAN EFEKTIFITAS ANTARA PEMBERIAN LAKTULOSA, PROBIOTIK, KOMBINASI LAKTULOSA DAN PROBIOTIK TERHADAP ENSEFALOPATI HEPATIK PADA PASIEN SIROSIS HATI [PDF]

, 2015
PERBANDINGAN EFEKTIFITAS ANTARA PEMBERIANLAKTULOSA, PROBIOTIK, KOMBINASI LAKTULOSA DANPROBIOTIK TERHADAP ENSEFALOPATI HEPATIK PADA PASIENSIROSIS HATIPendahuluan: Ensefalopati hepatik (EH) merupakan salah satu komplikasi utama padapasien sirosis hati ...
WAHYUNI
core  

Pharmacologic modulation of experimental postischemic hepatic function [PDF]

, 1989
The present study, evaluated and compared the effects of SRI 63-441, a potent platelet activating factor antagonist, superoxide dismutase (SOD), an oxygen free radical scavenger, and ibuprofen, a cyclooxygenase inhibitor on hepatic function after 90 ...
Makowka, L, Mazzaferro, V, Ontell, SJ, Ove, P, Starzl, TE, Trager, J   +5 more
core   +2 more sources