Results 131 to 140 of about 35,561 (292)

A Novel Frameshift Variant c.1023_1029del (p.Asp342ArgfsTer54) Leading to Extended Incorrect Protein C Termini in HOMER2 Causing Autosomal Dominant Nonsyndromic Hearing Loss

Journal of Clinical Laboratory Analysis, EarlyView.
We identified a novel c.1023_1029del (p.Asp342ArgfsTer54) frameshift variant in the HOMER2 gene that causes ADNSHL in a Chinese family with progressive, post‐lingual sensorineural hearing loss. The c.1023_1029del variant deletes 7 nucleotides, leading to an extended incorrect protein C terminus and marks the sixth pathogenic (or likely pathogenic ...
Li‐Ting Peng, Wei‐Qian Wang, Sha‐Sha Huang, Min Liu, Su‐Yan Yang, Dong‐Yang Kang, Xiang Wang, Xue Gao, Yong‐Yi Yuan, Jin‐Cao Xu   +9 more
wiley   +1 more source

Tumor Habitats Based on Multiparametric MRI Distinguish Atypical Glioblastoma From Primary Central Nervous System Lymphoma: Imaging‐Pathologic Correlation

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Atypical glioblastoma (GBM) (minimal or no necrosis on MRI) and primary central nervous system lymphoma (PCNSL) are difficult to distinguish on MRI; whether tumor habitat can more accurately distinguish atypical GBM from PCNSL remains uncertain.
Meng‐nan Sun, Hui Wang, Yan‐ying Yang, Xiao‐jun Yu, Hai‐nan Li, Dan‐dan Fu, Dong‐Zhang, Ru‐yu Ai, Xiao‐yu Hua, Li‐chao Wang, Ming‐yao Lai, Chang‐zheng Shi, Lin‐bo Cai   +12 more
wiley   +1 more source

A Network Centered on the Visual‐Motor Cortex Is Critically Involved in Postural Abnormality in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Postural abnormality (PA) is a key motor symptom in Parkinson's disease (PD) that leads to disability and death. However, the pathophysiology underlying PA is still unknown. Objective The objective of this study was to explore the neural patterns behind PAs and measures toward functional restoration using repetitive transcranial ...
Zhuang Wu, Sha Zhu, Ronghua Hong, Zhuoyu Zhang, Yanzi Peng, Jingxing Zhang, Lizhen Pan, Qiang Guan, Yuhui Chen, Lingjing Jin   +9 more
wiley   +1 more source

A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: a replicated, randomized controlled clinical trial

Journal of Pain Research, 2019
Anna M Wahl,1 Daniel Bidstrup,1 Isabel G Smidt-Nielsen,1 Mads U Werner,2 Ole Hyldegaard,1,3 Per Rotbøll-Nielsen21Hyperbaric Unit, Department of Anesthesia, Head and Orthopedic Center, Rigshospitalet, Copenhagen University Hospitals, Copenhagen ...
Wahl AM, Bidstrup D, Smidt-Nielsen IG, Werner MU, Hyldegaard O, Rotbøll-Nielsen P   +5 more
doaj  

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

An Exploration of Motion‐Sampling Interactions in 3D MRI for Neuroimaging

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To investigate how rigid head motion interacts with 3D MRI k‐space sampling strategies and to introduce motion‐sampling plots as a framework for predicting motion artifacts. Methods We evaluated a range of motion‐sampling combinations across three sampling trajectories (Cartesian, stack‐of‐stars, kooshball) in both simulation and in ...
Sophie Schauman, Adam van Niekerk, Ola Norbeck, Henric Rydén, Enrico Avventi, Stefan Skare   +5 more
wiley   +1 more source

A Digital Phantom for MR Spectroscopy Data Simulation

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Simulated data is increasingly valued by researchers for validating MRS processing and analysis algorithms. However, there is no consensus on the optimal approaches for simulation models and parameters. This study introduces a novel MRS digital brain phantom framework, providing a comprehensive and modular foundation for MRS data ...
D. M. J. van de Sande, A. T. Gudmundson, S. Murali‐Manohar, C. W. Davies‐Jenkins, D. Simicic, G. Simegn, İ. Özdemir, S. Amirrajab, J. P. Merkofer, H. J. Zöllner, G. Oeltzschner, R. A. E. Edden   +11 more
wiley   +1 more source

Liver-Targeting and pH-Sensitive Sulfated Hyaluronic Acid Mixed Micelles for Hepatoma Therapy

International Journal of Nanomedicine, 2019
Zhi-peng Li,1,* Gui-xiang Tian,1,* Hong Jiang,1,* Rui-yan Pan,2 Bo Lian,1 Min Wang,1 Zhi-qin Gao,1 Bo Zhang,2 Jing-liang Wu1 1School of Bioscience and Technology, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2School of
Li Z, Tian G, Jiang H, Pan R, Lian B, Wang M, Gao Z, Zhang B, Wu J   +8 more
doaj  

Intermediate-dose immune tolerance induction outperforms with faster success, less bleeding, and no added cost in comparison with low dose: a multicenter randomized clinical trial

Research and Practice in Thrombosis and Haemostasis
Background: Low-dose (LD) or intermediate-dose (MD) immune tolerance induction (ITI) is effective in children with severe hemophilia A (SHA) with high-titer inhibitors (HTIs) and is attractive in countries with economic constraints. However, high-quality
Zhengping Li, Zekun Li, Xiaoling Cheng, Heng Zhang, Can Yang, Qian Xu, Zhenping Chen, Yingzi Zhen, Gang Li, Guoqing Liu, Wanru Yao, Min Zhou, Jiao Jin, Jie Huang, Yongjun Fang, Liangzhi Xie, Man-Chiu Poon, Runhui Wu   +17 more
doaj   +1 more source

Pixel Value Differencing Based Image Steganography using AES and SHA-2 Cryptography Method

, 2020
Jayeeta Majumder, Chittaranjan Pradhan
openalex   +1 more source