Results 81 to 90 of about 931,571 (297)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Las investigaciones recientes sobre la migración laboral femenina internacional

open access: yesCiencia Ergo Sum, 2008
El objetivo de este artículo es analizar las investigaciones que se han llevado a cabo, desde diversas disciplinas, sobre la migración laboral femenina internacional. Los estudios que se examinan han sido elaborados desde diversos campos disciplinarios:
María J. Rodríguez Shadow
doaj  

Combining the Improved RGB Water-Filling Algorithm With Penumbra Removal Technique for Shadow Removal From Digitized Images

open access: yesIEEE Access
This study proposes a novel and highly efficient approach for the comprehensive removal of shadows from digitized images that is applicable to a broad spectrum of image types, from document scans to natural scenes.
You-Chang Liu, Cheng-Ta Chuang
doaj   +1 more source

The ‘persona’ lives of Roman Catholic priests

open access: yesHTS Teologiese Studies/Theological Studies, 2018
This study aimed to provide an in-depth description and interpretation of African Roman Catholic Church priests’ experiences integrating African and Western worldviews into their lives and works as Roman Catholic Church priests through the lens of ...
James O. Juma   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Disrupting shadow in the prothoracic gland induced larval development arrest in the fall armyworm Spodoptera frugiperda

open access: yesFrontiers in Physiology
IntroductionThe juvenile hormone (JH) and 20-hydroxyecdysone (20E) are the central regulating hormones of insect development. The timing of their secretion usually leads to developmental transitions.MethodsThe developmental transitions were evaluated via
Mian-Zhi Wu   +8 more
doaj   +1 more source

Moser’s shadow problem

open access: yesL’Enseignement Mathématique, 2019
Moser's shadow problem asks to estimate the shadow function \mathfrak s_b(n) , which is the largest number such that for each bounded convex polyhedron P with
Lagarias, Jeffrey C.   +2 more
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Corruption, shadow economy and income inequality: evidence from Asia [PDF]

open access: yes, 2012
A number of recent studies for Latin America show that as the size of the informal economy grows, corruption is less harmful to inequality. We investigate if this relationship is equally compelling for developing countries in Asia where corruption ...
Kar, Saibal, Saha, Shrabani
core  

Shadows: A Phenomenological Analysis

open access: yesPhainomenon, 2020
Abstract Shadows are intriguing phenomena. They do not have mass or energy. So, they are unable to have some basic characteristics of the objects of which they are shadows: they cannot move by themselves and they cannot experience the same kind of changes.
openaire   +2 more sources

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