Results 61 to 70 of about 429,033 (302)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Private tutoring as shadow education: Comparative overview [PDF]
Zbornik Instituta za pedagoška istraživanjaPrivate supplementary tutoring in school subjects, which takes place outside of regular school classes and is paid, is not unfamiliar in many education systems.
Spasenović Vera
doaj +1 more source
A group of primary 4 students' perceptions of shadow education in their English language learning [PDF]
, 2016 In Hong Kong, many students receive shadow education which supplements mainstream education. They employ English private tutoring because of different reasons. They also hold different views towards shadow education in English learning.
Chung, Choi-yee, 鍾彩兒
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Volume 35, Number 2 - May 1955 [PDF]
, 1955 Volume 34, Number 2 - May 1955. 46 pages including covers and advertisements. Editor, This Concerns You Arrigan, Robert, A Complete Education Costello, Thomas, Writ on Habeans Corpus Riley, George, Trilogy - The Picture Riley, George, Light ...
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Enculturation of Art Value of Carving Decoration (Anthropological Studies of Preservation Efforts of Purwo Shadow Puppets in Wonogiri) [PDF]
, 2015 This research tends to highlight the symbolic and philosophic values of Purwo shadow puppets. Most of the study themes though emphasize its exhibition.
Subiyantoro, S. (Slamet) +2 more
core
Shadow Education as Sociological Field
, 2023 Research on curriculum and shadow education (also known as private or supplementary tutoring) is increasing and diversifying. Shadow education can be understood as out-of-school formal education. Although separate from the school program, it is directed toward that program. Shadow education often targets aspects of the curriculum of mass schooling that
openaire +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The impact of economic globalization on the shadow economy in Egypt
, 2017 This study examines the economic globalization and the shadow economy nexus in Egypt. Using time series data from 1976 to 2013, the impulse response analysis shows that the response of the shadow economy in Egypt to positive shocks in economic ...
Farzanegan, Mohammad Reza, Hassan, Mai
core +2 more sources