Results 31 to 40 of about 47,342 (264)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
The article explores the notions related to the perception of the figure/ground contrast in the visual arts. Starting from the history of the words “negative” and “depth of field” in 19th-century photography, it studies solutions such as the possible ...
Marie-Madeleine Martinet
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Extension and the Ground in Motion’s Gestalt: Literal and metaphoric
We propose that in pictures both the extended limbs of actors and the ground are involved in gestalts for movement. Limbs extend to suggest more motion literally when a dancer is in air and refer to a canonical pose when on the ground.
Mastandrea Stefano, Kennedy John M.
doaj +1 more source
The Effect of Negative Samples on the Accuracy of Water Body Extraction Using Deep Learning Networks
Water resources are important strategic resources related to human survival and development. Water body extraction from remote sensing images is a very important research topic for the monitoring of global and regional surface water changes.
Jia Song, Xiangbing Yan
doaj +1 more source
Liouville’s imaginary shadow [PDF]
Abstract $ \mathcal{N}=1 $ super Liouville field theory is one of the simplest non-rational conformal field theories. It possesses various important extensions and interesting applications, e.g. to the AGT relation with 4D gauge theory or the construction of the OSP(1|2) WZW model.
Schomerus, V., Suchanek, P.
openaire +4 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
ver. 3: changed title, and changed terminology throughout the paper, using "spectrahedral shadows" instead of "sdp representable sets".
openaire +2 more sources
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source

