Combining biosensor and metabolic network optimization strategies for enhanced L-threonine production in Escherichia coli. [PDF]
Zhao Z+9 more
europepmc +1 more source
Enzymatic Production of Opine‐type Chiral Amines with Controlled Stereoselectivity
Chiral secondary amine dicarboxylic acid derivatives are key building blocks of several peptidomimetic angiotensin‐converting enzyme (ACE2) inhibitors. Reductive amination of α‐keto acids with α‐amino esters can yield orthogonally functionalized derivatives facilitating further chemical modifications. Biocatalysis offers a sustainable and selective way
András Telek+5 more
wiley +1 more source
Enhancing High-Level Food-Grade Expression of Glutamate Decarboxylase and Its Application in the Production of γ-Aminobutyric Acid. [PDF]
Zhang K+5 more
europepmc +1 more source
Mitochondria‐Catalyzed Activation of Anticancer Prodrugs
Mitochondria mediate electron transport chain (ETC) to power ATP synthase. In cancer cells, the ETC is disturbed leading to leakage of electron that ultimately results in generation of H2O2. This difference between cancer and healthy cells can be used for the design of cancer‐specific prodrugs as confirmed in several proof‐of‐concept studies ...
Michael Raucheisen+7 more
wiley +1 more source
Acetate production from corn stover hydrolysate using recombinant Escherichia coli BL21 (DE3) with an EP-bifido pathway. [PDF]
Zhu J+15 more
europepmc +1 more source
Green Highly Porous Bio‐Zr‐MOF/Fabric Composites for Organophosphonates Detoxification
Discover a sustainable solution for tackling toxic organophosphates. Using bio‐based linkers and water as a solvent, we synthesize eco‐friendly Zr‐fumarate and MIP‐202 composites on fabric, achieving enhanced degradation rates. These composites outperform traditional MOFs like UiO‐66‐NH2, rapidly breaking down harmful chemicals, with applications in ...
Mai O. Abdelmigeed+3 more
wiley +1 more source
Establishment & characterization of a non-adherent insect cell line for cultivated meat. [PDF]
Letcher SM+5 more
europepmc +1 more source
Unlocking Potential: Vegetable Oil Effects on Lactic Acid Extraction
This study investigates the recovery of lactic acid from aqueous solutions using tri‐n‐octylamine (TOA) and various vegetable oils. The highest separation efficiency (74.54 %) and distribution coefficient (2.93) were achieved with rice bran oil. PCA analysis reveals that sesame and rice bran oils are highly similar, offering efficient extraction ...
Mustafa Kanbur+2 more
wiley +1 more source
The physiology of an engineered Saccharomyces cerevisiae strain that carries both an improved glycerol-3-phosphate and the synthetic dihydroxyacetone pathway for glycerol utilization. [PDF]
Perpelea A+6 more
europepmc +1 more source
Characterization of Aspergillus oryzae mutant and its application in heterologous lipase expression. [PDF]
Li Q+6 more
europepmc +1 more source