Results 231 to 240 of about 22,410 (289)

Combination of Lenvatinib and Antibiotics: A Potential Approach to Enhance Sensitivity in Differentiated Thyroid Cancer

International Journal of Cancer, EarlyView.
Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger, Petra Huber‐Cantonati, Daniela D. Weber, Sarah Pichler, Georg Schischkow, Marta Garcia‐Miralles, Christian Pirich, Gundula Rendl, Teresa Kiener, Thomas Felder, Martin Geroldinger, Robert Terkola, Barbara Kofler, Johanna Pachmayr   +13 more
wiley   +1 more source

Engineering a heme-dependent tryptophan hydroxylase pathway in <i>E. coli</i> for enhanced melatonin production. [PDF]

Synth Syst Biotechnol
Zhang L, Yin G, Pan S, Zheng X, Zhou S, Du G, Li J, Chen J, Xu R, Kang Z.   +9 more
europepmc   +1 more source

Development of a Novel 18F‐Labeled Radioligand for Imaging Translocator Protein With Positron Emission Tomography

iRADIOLOGY, EarlyView.
Translocator protein 18 kDa (TSPO) is a well‐established biomarker of neuroinflammation and is implicated in the pathophysiology of various neurodegenerative diseases. This study presents [18F]TSPO‐1118 ([18F]3) as a promising positron emission tomography (PET) radioligand for imaging TSPO with high affinity, robust brain uptake, and specificity in ...
Jian Rong, Chunyu Zhao, Xin Zhou, Jiahui Chen, Yabiao Gao, Zhendong Song, Yinlong Li, Zijing Li, Steven H. Liang   +8 more
wiley   +1 more source

Biological-chemical method for synthesizing <i>p</i>-menthane-3,8-diol. [PDF]

Synth Syst Biotechnol
Zuo X, Zhang H, Zhang Z, Ma Y, Zhang C, Lu W.   +5 more
europepmc   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

Scaled up fed-batch production of recombinant alpha-1-antitrypsin by CHO cells in single-use surface aerated orbital shaken bioreactor. [PDF]

Sci Rep
Tang WQ, Jiang CQZ, Zheng ZY, Lau A, Bi X, Zhang W, Ng SK.   +6 more
europepmc   +1 more source

Antibiotic-Free Expression of γ-Glutamyl Transpeptidase in <i>Bacillus subtilis</i> and Process Optimization for L-Theanine Separation and Purification. [PDF]

Molecules
Zhang R, Jiang B, Xiao Z, Xiang L.
europepmc   +1 more source

Valorization of Carrot Pomace into Mycelium-Based Paper for Packaging Applications. [PDF]

ACS Omega
Mousavi SN, Kalita NK, Lindstrom Ramamoorthy SK, Hakkarainen M, Zamani A.   +4 more
europepmc   +1 more source

Development of <i>Saccharomyces cerevisiae</i> isobutanol production strain from osmotolerant and ethanol-producing industrial isolated yeast. [PDF]

Biotechnol Rep (Amst)
Thammapanyaphong N, Boonyanuwat M, Luengnaruemitchai A, Koonthongkaew J.   +3 more
europepmc   +1 more source

<i>De novo</i> biosynthesis of 1,5-diamino-2-hydroxypentane from glucose via combination of fermentation and whole-cell catalysis. [PDF]

Synth Syst Biotechnol
Zheng Z, Chen Z, Tang T, Lu H, Xu Q, Yang Z, Liu W, Wu C, Hu S, Chen F, Zhang A, Chen K.   +11 more
europepmc   +1 more source