Results 51 to 60 of about 224,134 (302)

Equivalent frame modelling of an unreinforced masonry building with flexible diaphragms - a case study [PDF]

, 2016
A case study was conducted to investigate the applicability of the equivalent frame modelling for the nonlinear time-history analysis of unreinforced masonry buildings with flexible diaphragms.
Derakhshan, H., Griffith, M., Ingham, J., Nakamura, Y., Sheikh, A.   +4 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Shaking table tests on spherical sliding bearings taking eccentricity and uplift into account

Japan Architectural Review, 2019
Although rubber bearings are popular in Japan as seismic isolation bearings, spherical sliding bearings (SSBs) or friction pendulum bearings are widely used in many countries, including the U.S.
Toru Takeuchi, Hideji Nakamura, Masakaze Uchida, Michiyasu Yoshida, Ryota Matsui   +4 more
doaj   +1 more source

Numerical simulation on seismic behavior of mechanical structure for electronic equipment with bolted joints

Nihon Kikai Gakkai ronbunshu, 2019
To stably operate electronic equipment such as computers and networking devices is essential to the current information society. They should be stably operated even when they are being subjected to seismic excitations. The computers and other devices are
Keisuke KANANO, Takuzo YAMASHITA, Daigoro ISOBE   +2 more
doaj   +1 more source

Numerical studies on the seismic response of a three-storey low-damage steel framed structure incorporating seismic friction connections

Resilient Cities and Structures, 2023
A 9 m high, near full scale three-storey configurable steel frame composite floor building incorporating friction-based connections is to be tested using two linked bi-directional shake tables at the International joint research Laboratory of Earthquake ...
Zhenduo Yan, Shahab Ramhormozian, G. Charles Clifton, Rui Zhang, Ping Xiang, Liang-Jiu Jia, Gregory A. MacRae, Xianzhong Zhao   +7 more
doaj   +1 more source

Seismic Performance of Anchored Brick Veneer [PDF]

, 2009
A study was conducted on the out-of-plane seismic performance of anchored brick veneer with wood-frame backup wall systems, to evaluate prescriptive design requirements and current construction practices.
LaFave, James M., Reneckis, Dziugas Joseph   +1 more
core  

Long term monitoring and field testing of an innovative multi-storey timber building [PDF]

, 2011
Peer ...
Kohli, Varun, Morris, Hugh, Omenzetter, Piotr, Uma, S R, Worth, Margaret   +4 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Structural health monitoring of high voltage electrical switch ceramic insulators in seismic areas [PDF]

, 2014
High voltage electrical switches are crucial components to restart rapidly the electrical network right after an earthquake. But there currently exists no automatic procedure to check if these ceramic insulators have suffered after an earthquake, and ...
BARTHES, Clément, MECHBAL, Nazih, MOSALAM, Khalid M., REBILLAT, Marc   +3 more
core   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source