Results 61 to 70 of about 224,134 (302)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Centrifuge model tests on suffusion-induced deterioration and its consequences in seismic response of levees

Soils and Foundations
Shake table tests on a levee deteriorated by seepage-induced internal erosion are performed in a geotechnical centrifuge to investigate the effects of erosion-induced heterogeneity and mechanical characteristics change on the seismic response of the ...
Akihiro Takahashi, Tamaki Inoue, Saki Yamagata, Kazuki Horikoshi   +3 more
doaj   +1 more source

Seismic Performance of Steel Pipe Pile to Cap Beam Moment Resisting Connections [PDF]

, 2013
INE/AUTC 13 ...
Fulmer, Steven J., Kowalsky, Mervyn J., Nau, James M.   +2 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Seismic performance of concrete tunnel–sand–pile interaction by the shake table test

Deep Underground Science and Engineering
This research presents the square root sum of squares response of displacements and tunnel moments under the Kobe and Loma Prieta seismic excitations with a peak ground acceleration of 0.05 g for various dry relative densities of local sand in Bangladesh.
Md. Foisal Haque, Mehedi A. Ansary
doaj   +1 more source

6 Seconds of Sound and Vision: Creativity in Micro-Videos

, 2014
The notion of creativity, as opposed to related concepts such as beauty or interestingness, has not been studied from the perspective of automatic analysis of multimedia content.
Hare, Neil O, Jaimes, Alejandro, Redi, Miriam, Schifanella, Rossano, Trevisiol, Michele   +4 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

PEER Testbed Study on a Laboratory Building: Exercising Seismic Performance Assessment [PDF]

, 2005
From 2002 to 2004 (years five and six of a ten-year funding cycle), the PEER Center organized the majority of its research around six testbeds. Two buildings and two bridges, a campus, and a transportation network were selected as case studies to ...
Beck, James L., Chang, Stephanie E., Chaudhuri, Samit Ray, Comerio, Mary C., Falit-Baiamonte, Anthony, Holmes, William T., Hutchinson, Tara, Konstantinidis, Dimitrios, Lee, Tae-Hyung, Makris, Nicos, Mosalam, Khalid, Porter, Keith A., Shaikhutdinov, Rustem, Smith, Ryan, Somerville, Paul, Stallmeyer, John C.   +15 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Seismic isolation of small modular reactors using metamaterials

AIP Advances, 2018
Adaptation of metamaterials at micro- to nanometer scales to metastructures at much larger scales offers a new alternative for seismic isolation systems. These new isolation systems, known as periodic foundations, function both as a structural foundation
Witarto Witarto, S. J. Wang, C. Y. Yang, Xin Nie, Y. L. Mo, K. C. Chang, Yu Tang, Robert Kassawara   +7 more
doaj   +1 more source