Results 81 to 90 of about 505,096 (311)

Detection and clearing of trapped ions in the high current Cornell photoinjector

open access: yes, 2015
We have recently performed experiments to test the effectiveness of three ion-clearing strategies in the Cornell high intensity photoinjector: DC clearing electrodes, bunch gaps, and beam shaking.
Bartnik, Adam   +5 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Design on the Shaking Table Test for Ground Crack Dynamic Response under Earthquake

open access: yesChemical Engineering Transactions, 2016
In this paper, according to a particular ground fissures in Xi’an city in the south of the actual stratigraphic profiles use a similar role of strong earthquakes and the theory of vibration table crack mechanical response model test for similar relation ...
M.M. Liu, F.F. Dong
doaj   +1 more source

Simplified Estimation of Economic Seismic Risk for Buildings [PDF]

open access: yes, 2004
A seismic risk assessment is often performed on behalf of a buyer of commercial buildings in seismically active regions. One outcome of the assessment is that a probable maximum loss (PML) is computed.
Beck, James L.   +2 more
core   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Seismic response of micropiles-reinforced landslide based on shaking table test

open access: yesGeomatics, Natural Hazards & Risk, 2019
A series of shaking table tests were conducted on unreinforced and micropiles-reinforced soil landslides to investigate the seismic response of micropiles-reinforced landslide and the dynamic mechanical behaviour of micropiles in landslide under ...
Nan Li   +5 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Effects of flux application and melting parameters in investment casting of pure aluminium by in-situ melting technique [PDF]

open access: yes, 2018
Investment cast aluminium suffers porosity defect attributed to the complex combination of various factors including melt quality, casting process parameter and pouring technique.
Saleh, Aslinda
core  

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

open access: yesAdvanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian   +4 more
wiley   +1 more source

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