Results 31 to 40 of about 890,345 (290)

Therapies for Mitochondrial Disorders

open access: yesSURE Journal: (Science Undergraduate Research Experience Journal), 2022
Mitochondria are cytoplasmic, double-membrane organelles that synthesise adenosine triphosphate (ATP). Mitochondria contain their own genome, mitochondrial DNA (mtDNA), which is maternally inherited from the oocyte.
Kayli Sousa Smyth, Anne Mulvihill
doaj   +1 more source

Synergy Assessment of Four Antimicrobial Bioactive Compounds for the Combinational Treatment of Bacterial Pathogens

open access: yesBiomedicines, 2023
Antimicrobial resistance (AMR) has become a topic of great concern in recent years, with much effort being committed to developing alternative treatments for resistant bacterial pathogens.
Kevin Masterson   +3 more
doaj   +1 more source

Boltzmann-Shannon Entropy: Generalization and Application [PDF]

open access: yes, 2006
The paper deals with the generalization of both Boltzmann entropy and distribution in the light of most-probable interpretation of statistical equilibrium. The statistical analysis of the generalized entropy and distribution leads to some new interesting
Aczel J.   +17 more
core   +2 more sources

The potential of stem cell therapy in Multiple Sclerosis treatment: a review

open access: yesSURE Journal: (Science Undergraduate Research Experience Journal), 2023
Multiple Sclerosis is an autoimmune and neurodegenerative disease of the central nervous system. There are currently 2.8 million people living with Multiple Sclerosis worldwide, including 9000 people in Ireland, with a prevalence of 193 per 100,000 ...
Sorina Amarculesei   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Melittin: A Natural Component of Honeybee Venom as a Potential Anti-Cancer Therapy

open access: yesSURE Journal: (Science Undergraduate Research Experience Journal), 2023
Cancer is a major cause of death worldwide and while chemotherapy is the main approach there are many negative associations in current treatment procedures. These include lack of selectivity, side effects and drug resistance.
Niamh Donnellan, Anne M Friel
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

A Novel Framework for Smart Cyber Defence: A Deep-Dive Into Deep Learning Attacks and Defences

open access: yesIEEE Access, 2023
Deep learning techniques have been widely adopted for cyber defence applications such as malware detection and anomaly detection. The ever-changing nature of cyber threats has made cyber defence a constantly evolving field.
Iram Arshad   +4 more
doaj   +1 more source

Kalman meets Shannon [PDF]

open access: yes, 2015
We consider the problem of communicating the state of a dynamical system via a Shannon Gaussian channel. The receiver, which acts as both a decoder and estimator, observes the noisy measurement of the channel output and makes an optimal estimate of the ...
Gattami, Ather
core  

A Minimal Set of Shannon-type Inequalities for Functional Dependence Structures

open access: yes, 2017
The minimal set of Shannon-type inequalities (referred to as elemental inequalities), plays a central role in determining whether a given inequality is Shannon-type. Often, there arises a situation where one needs to check whether a given inequality is a
Chan, Terence   +2 more
core   +1 more source

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