Results 51 to 60 of about 6,713,628 (313)

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Optimal Control of Wave Energy Dissipation via a Mobile Damping Actuator

Mathematics
This work studies an optimal control problem for a wave equation with a moving localized damping, modeled by the characteristic function of a ball whose center evolves according to a controlled second-order dynamical system.
Ahmed Bchatnia, Saleh Fahad Aljurbua
doaj   +1 more source

Shape derivative of cost function for singular point: Evaluation by the generalized J integral

JSIAM Letters, 2014
This paper presents analytic solutions of the shape derivatives (Fréchet derivatives with respect to domain variation) for singular points of cost functions in shape-optimization problems for the domain in which the boundary value problem of a partial ...
H. Azegami, K. Ohtsuka, M. Kimura
semanticscholar   +1 more source

A probabilistic approach to shape derivatives

Numerische Mathematik
Abstract We introduce a novel mesh-free and direct method for computing the shape derivative in PDE-constrained shape optimization problems. Our approach is based on a probabilistic representation of the shape derivative and is applicable for second-order semilinear elliptic PDEs with Dirichlet boundary conditions and a general class ...
Schlegel, Luka, Schulz, Volker, Seifried, Frank T., Würschmidt, Maximilian   +3 more
openaire   +2 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Variational approach to shape derivatives [PDF]

ESAIM: Control, Optimisation and Calculus of Variations, 2008
Summary: A general framework for calculating shape derivatives for optimization problems with partial differential equations as constraints is presented. The proposed technique allows to obtain the shape derivative of the cost without the necessity to involve the shape derivative of the state variable. In fact, the state variable is only required to be
Ito, Kazufumi, Kunisch, Karl, Peichl, Gunther H.   +2 more
openaire   +2 more sources

The Gateau derivative of cost functions in the optimal shape problems and the existence of the shape derivatives of solutions of the Stokes problems

JSIAM Letters, 2009
openaire   +4 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Computation of Shape Derivatives in Electromagnetic Shaping by Algorithmic Differentiation

Journal of Mathematical Study, 2019
Shape optimization based on analytical shape derivatives is meanwhile a well-established tool in engineering applications. For an appropriate discretization of the underlying problem, the technique of algorithmic differentiation can also be used to provide a discrete analogue of the analytic shape derivative.
Eppler, Karsten, Harbrecht, Helmut, Schlenkrich, Sebastian, Walther, Andrea   +3 more
openaire   +2 more sources

Lagrange method in shape optimization for non-linear partial differential equations: A material derivative free approach [PDF]

, 2013
This paper studies the relationship between the material derivative method, the shape derivative method, the min-max formulation of Correa and Seeger, and the Lagrange method introduced by Céa.
Sturm, Kevin
core   +1 more source