Results 51 to 60 of about 974,120 (307)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Exterior Shape Factors From Interior Shape Factors
, 2019 Shape factors for steady heat conduction enable quick and highly simplified calculations of heat transfer rates within bodies having a combination of isothermal and adiabatic boundary conditions.
Lienhard, John H
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Shape-Based Generative Modeling for de Novo Drug Design
, 2019 In this work, we propose a machine learning approach to generate novel molecules starting from a seed compound, its three-dimensional (3D) shape, and its pharmacophoric features.
José Jiménez (1600390) +3 more
core +3 more sources
Design of Dielectric Elastomer Actuator and Its Application in Flexible Gripper
MicromachinesDielectric elastomer actuators (DEAs) are difficult to apply to flexible grippers due to their small deformation range and low output force. Hence, a DEA with a large bending deformation range and output force was designed, and a corresponding flexible ...
Xiaoyu Meng +8 more
doaj +1 more source
Design and Measurement of a Dual FBG High-Precision Shape Sensor for Wing Shape Reconstruction
Sensors, 2021 FBG shape sensors based on soft substrates are currently one of the research focuses of wing shape reconstruction, where soft substrates and torque are two important factors affecting the performance of shape sensors, but the related analysis is not ...
Huifeng Wu +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Alexandria Engineering Journal, 2022 System design is a complicated and iterative process. Accordingly, a robust optimization procedure should be involved during the design process to minimize complications and time consumed for the whole process.
Loai A. Elmahdi +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source