Results 161 to 170 of about 8,058,581 (353)

Shape Analysis in Bioinformatics [PDF]

open access: yes, 2009
In this thesis we explore two main themes, both of which involve proteins. The first area of research focuses on the analyses of proteins displayed as spots on 2-dimensional planes.
Petty, Emma Marie
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Molecular Shape-Preserving Au Electrode for Progesterone Detection

open access: yesSensors
Quantifying progesterone levels in the body is an important indicator of early pregnancy and health. Molecular shape-preserving electrodes have garnered attention in electrochemical biosensors because they can detect targets without the need for ...
Fukuto Soyama   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

On Using Physical Analogies for Feature and Shape Extraction in Computer Vision

open access: yes, 2011
There is a rich literature of approaches to image feature extraction in computer vision. Many sophisticated approaches exist for low- and for high-level feature extraction but can be complex to implement with parameter choice guided by experimentation ...
Hurley, David   +3 more
core  

Unsupervised Anomaly Detection on Implicit Shape Representations for Sarcopenia Detection

open access: yes2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)
Sarcopenia is an age-related progressive loss of muscle mass and strength that significantly impacts daily life. A commonly studied criterion for characterizing the muscle mass has been the combination of 3D imaging and manual segmentations. In this paper, we instead study the muscles' shape.
Louise Piecuch   +5 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Foreground detection of video through the integration of novel multiple detection algorithims [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityThe main outcomes of this research are the design of a foreground detection algorithm, which is more accurate and less time consuming than existing ...
Nawaz, Muhammad
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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