Results 81 to 90 of about 1,732,484 (345)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Vision-based weed identification with farm robots [PDF]

, 2010
Robots in agriculture offer new opportunities for real time weed identification and quick removal operations. Weed identification and control remains one of the most challenging task in agriculture, particularly in organic agriculture practices ...
Bochtis, Dionysis, Green, Ole, Nørremark, Michael, Swain, Kishore C., Sørensen, Claus Grøn   +4 more
core  

mRNA Fragmentation Pattern Detected by SHAPE

Current Issues in Molecular Biology
The success of messenger RNA (mRNA) vaccines in controlling COVID-19 has warranted further developments in new technology. Currently, their quality control process largely relies on low-resolution electrophoresis for detecting chain breaks. Here, we present an approach using multi-primer reverse transcription sequencing (MPRT-seq) to identify ...
Shanshan Feng, Ting Chen, Yunlong Zhang, Changrui Lu   +3 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

DentalArch: AI-Based Arch Shape Detection in Orthodontics

Applied Sciences
Objective: This study aims to introduce and assess a novel AI-driven tool developed for the classification of orthodontic arch shapes into square, ovoid, and tapered categories.
J. D. Tamayo-Quintero, J. B. Gómez-Mendoza, S. V. Guevara-Pérez   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Recognition and Classification of Typical Building Shapes Based on YOLO Object Detection Models

ISPRS International Journal of Geo-Information
The recognition and classification of building shapes are the prerequisites and foundation for building simplification, matching, and change detection, which have always been important research problems in the field of cartographic generalization. Due to
Xiao Wang, Haizhong Qian, Limin Xie, Xu Wang, Bohao Li   +4 more
doaj   +1 more source

Night Time Vehicle Detection

Journal of Intelligent Systems, 2012
Night driving is one of the major factors which affects traffic safety. Although detecting oncoming vehicles at night time is a challenging task, it may improve traffic safety.
Fleyeh Hasan, Mohammed Iman A.
doaj   +1 more source