Results 91 to 100 of about 1,732,484 (345)

Shape based kinetic outlier detection in real-time PCR

open access: yesBMC Bioinformatics, 2010
Background Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time PCR assumes that the compared samples have similar PCR efficiency.
D'Atri Mario   +5 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

THE FUSION OF EDGE DETECTION AND MATHEMATICAL MORPHOLOGY ALGORITHM FOR SHAPE BOUNDARY RECOGNITION

open access: yesJournal of ICT, 2016
Edge detection is important in image analysis to form the shape of an object. Edge is the boundary between different textures, which helps with object segmentation and recognition. Currently, several edge detection techniques are able to identify objects
Mahmod Othman   +4 more
doaj  

A general algorithm for manipulating non-linear and linear entanglement witnesses by using exact convex optimization

open access: yes, 2009
A generic algorithm is developed to reduce the problem of obtaining linear and nonlinear entanglement witnesses of a given quantum system, to convex optimization problem.
Bailey R A   +19 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A hybrid Exponential-Gaussian approach for pulse shape modeling in liquid scintillators

open access: yesNuclear Engineering and Technology
We present a bi-Exponential-Gaussian Hybrid (EGH-2) model to quantitatively characterize scintillation pulse shapes generated by neutrons and γ-rays in the BC501A organic liquid scintillator detector. Pulses were recorded digitally from a mixed radiation
Harleen Singh, Rohit Mehra
doaj   +1 more source

Line-Constrained Shape Feature for Building Change Detection in VHR Remote Sensing Imagery

open access: yesISPRS International Journal of Geo-Information, 2018
Buildings represent the most relevant features of human activity in urban regions, but their change detection using very-high-resolution (VHR) remote sensing imagery is still a major challenge. Effective representation of the building is the key point in
Haifei Liu   +4 more
doaj   +1 more source

A Self-Organizing Neural Scheme for Door Detection in Different Environments

open access: yes, 2012
Doors are important landmarks for indoor mobile robot navigation and also assist blind people to independently access unfamiliar buildings. Most existing algorithms of door detection are limited to work for familiar environments because of restricted ...
Kunwar, F., Mahmood, F.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Deep Learning for Live Cell Shape Detection and Automated AFM Navigation. [PDF]

open access: yesBioengineering (Basel), 2022
Rade J   +5 more
europepmc   +1 more source

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