Results 111 to 120 of about 8,058,581 (353)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

3D time series analysis of cell shape using Laplacian approaches [PDF]

open access: yes, 2013
Background: Fundamental cellular processes such as cell movement, division or food uptake critically depend on cells being able to change shape. Fast acquisition of three-dimensional image time series has now become possible, but we lack efficient tools
Stephens, Len R.   +7 more
core   +1 more source

Recognition and Classification of Typical Building Shapes Based on YOLO Object Detection Models

open access: yesISPRS International Journal of Geo-Information
The recognition and classification of building shapes are the prerequisites and foundation for building simplification, matching, and change detection, which have always been important research problems in the field of cartographic generalization. Due to
Xiao Wang   +4 more
doaj   +1 more source

Shape based kinetic outlier detection in real-time PCR

open access: yesBMC Bioinformatics, 2010
Background Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time PCR assumes that the compared samples have similar PCR efficiency.
D'Atri Mario   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Towards Shape Understanding through Non-Parametric Shape Warping

open access: yes, 2009
This paper pursues the idea of understanding shapes of unknown objects through establishing correspondence with points from the surface of known objects. A lot of geometryrelated knowledge, such as functionally correct grasps or object constellations,
Hillenbrand, Ulrich
core  

Insignificant shadow detection for video segmentation

open access: yes, 2005
To prevent moving cast shadows from being misunderstood as part of moving objects in change detection based video segmentation, this paper proposes a novel approach to the cast shadow detection based on the edge and region information in multiple frames.
Tang, X.   +14 more
core   +1 more source

Pedestrian detection in uncontrolled environments using stereo and biometric information [PDF]

open access: yes, 2006
A method for pedestrian detection from challenging real world outdoor scenes is presented in this paper. This technique is able to extract multiple pedestrians, of varying orientations and appearances, from a scene even when faced with large and multiple
O'Connor, Noel E.   +7 more
core   +1 more source

THE FUSION OF EDGE DETECTION AND MATHEMATICAL MORPHOLOGY ALGORITHM FOR SHAPE BOUNDARY RECOGNITION

open access: yesJournal of ICT, 2016
Edge detection is important in image analysis to form the shape of an object. Edge is the boundary between different textures, which helps with object segmentation and recognition. Currently, several edge detection techniques are able to identify objects
Mahmod Othman   +4 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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