Results 61 to 70 of about 4,605,857 (269)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Computational Methods for Shape Manipulation in generation : a literature review [PDF]
, 2010 In this paper we will present a state of the art of the descriptive and generative models for shape. We will present several different approaches for the manipulation of shape in computational systems: numerical models, graph models, descriptive models ...
AOUSSAT, Améziane +3 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
4-Axis CNC emulation with dual legacy KUKA robots via G-code-to-KRL translation
International Journal of Advanced Robotic SystemsThis paper presents a feasibility-oriented study on the implementation of a coordinated dual-robot workflow using two legacy KUKA industrial robots (KR16 and KR5) for CNC-style low-load machining tasks.
Paúl A. Chasi-Pesántez +5 more
doaj +1 more source
Effect of Dimension and Shape of Magnet on the Performance AC Generator with Translation Motion
IOP Conference Series: Materials Science and Engineering, 2018 Abstract The development of power plants using the renewable energy sources is very rapid. Renewable energy sources used solar energy, wind energy, ocean wave energy and other energy. All of these renewable energy sources require a processing device or a change of motion system to become electrical energy.
A. Indriani, S. Dimas, null Hendra
openaire +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Morphological shape generation through user-controlled group metamorphosis [PDF]
, 2013 Morphological shape design is interpreted in this paper as a search for new shapes from a particular application domain represented by a set of selected shape instances.
Fryazinov, Oleg +3 more
core +1 more source
Nature CommunicationsDespite centuries of investigation, bubbles continue to unveil intriguing dynamics relevant to a multitude of practical applications, including industrial, biological, geophysical, and medical settings.
Jian H. Guan +4 more
doaj +1 more source