Results 41 to 50 of about 1,674,290 (282)

Using shape grammars as a rule based approach in urban planning - a report on practice

, 2011
With the development of user friendly software, using procedural shape grammars has become productive for urban planning projects. Little about the experience of their use by architects and urban planning agencies has been reported yet.
P. Schirmer, Schirmer, Patrick, N. Kawagishi, Kawagishi, Noboru   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Multi-Domain Recognition of Hand-Drawn Diagrams Using Hierarchical Parsing

Multimodal Technologies and Interaction, 2020
This paper presents an approach for the recognition of multi-domain hand-drawn diagrams, which exploits Sketch Grammars (SkGs) to model the symbols’ shape and the abstract syntax of diagrammatic notations.
Vincenzo Deufemia, Michele Risi
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Extraction and evaluation of transportation network grammars for efficient planning applications

Design Science, 2018
Grammars, with their generic approach and broad application potential in many planning fields, are accepted as adaptable and efficient tools for design and planning applications, bridging design rules and technical planning requirements.
B. J. Vitins, K. W. Axhausen
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Computational Design and Service Learning in Informal Settlement Planning: A Pedagogical Model for Architectural Education

Buildings
Rapid urbanization in the Global South continues to intensify the growth of informal settlements, challenging architectural education to equip students with methods capable of addressing complex socio-spatial, environmental, and ethical conditions. While
Fernando Lima, Anna Agnew, Emily Schiedemeyer, Vira Williams   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Empirical Risk Minimization for Probabilistic Grammars: Sample Complexity and Hardness of Learning [PDF]

, 2012
Probabilistic grammars are generative statistical models that are useful for compositional and sequential structures. They are used ubiquitously in computational linguistics.
Noah A. Smith, Smith, N. A., Shay B. Cohen, Cohen, S. B.   +3 more
core   +1 more source