Results 41 to 50 of about 2,232 (295)
Languages of flexibility: : Digital grammars of architecture, 1970s [PDF]
At the same time that flexibility was being constructed as the potential to rearrange, repurpose and even reclaim spaces within modernism, the 1960s and 70s saw the technical concretisation of a parallel conception of design as an open system, into a ...
Miranda Carranza, Pablo,
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Extraction and evaluation of transportation network grammars for efficient planning applications
Grammars, with their generic approach and broad application potential in many planning fields, are accepted as adaptable and efficient tools for design and planning applications, bridging design rules and technical planning requirements.
B. J. Vitins, K. W. Axhausen
doaj +1 more source
Shape grammars for architectural design: the need for reframing [PDF]
Although many shape grammars and corresponding implementations have been proposed, shape grammars are not widely adopted by architectural designers.
De Meyer, Ronald +7 more
core +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Rapid urbanization in the Global South continues to intensify the growth of informal settlements, challenging architectural education to equip students with methods capable of addressing complex socio-spatial, environmental, and ethical conditions. While
Fernando Lima +3 more
doaj +1 more source
Engineering Grammar-Based Type Checking for Graph Rewriting Languages
The ability to handle evolving graph structures is important both for programming languages and modeling languages. Of various languages that adopt graphs as primary data structures, a graph rewriting language LMNtal provides features of both (concurrent)
Naoki Yamamoto, Kazunori Ueda
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Computation-friendly shape grammars [PDF]
NP-hardness of parametric subshape recognition for an arbitrary number of open terms is proven. Guided by this understanding of the complexity of subshape recognition, a framework for computation-friendly parametric shape grammar interpreters is proposed,
Kui Yue (5047310) +2 more
core +1 more source

