Results 51 to 60 of about 2,232 (295)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Design and study of urban form using shape grammars [PDF]
The main goal of this paper is to present shape grammars as an analytical tool to study urban morphology and as a design tool for urban planning. Shape grammars emerged in the 70s through the seminal article by Stiny & Gips, and are used to analyse past ...
Sara Eloy (5995706)
core +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
KITOPARTS: A Virtual Playground To Explore Form, Space, & Order
Architecture students use both analog and digital tools throughout their design process. Ideally, the affordances of each tool complement each other. Our goal with Kitoparts is to move beyond two-dimensional screen based computer modeling environments to
Derek A. Ham
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Transforming Grammars for Goal Driven Style Innovation [PDF]
Shape grammar transformations have been used for developing new design styles by the systematic modification of grammars that encode existing styles. We make use of a style description scheme to aid grammar transformations for goal driven style change. A
S.C. Chase, S. Ahmad
core
Attribute Multiset Grammars for Global Explanations of Activities [PDF]
Recognizing multiple interleaved activities in a video requires implicitly partitioningthe detections for each activity. Furthermore, constraints between activities are impor-tant in finding valid explanations for all detections.
David Hogg +3 more
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Architectural design with simple shape grammars and learning
This work presents a proposal for the automatic generation of architectural design. This scheme is based on the training of simple shape grammars through reinforcement learning technics.
Eduardo Jiménez-Morales +5 more
doaj
Implementation issues of parallel shape grammars [PDF]
Shape grammars come in a variety of forms. Algebras of shapes have been defined for spatial elements of different kinds, as well as for shapes augmented with varying attributes, allowing for grammar forms to be expressed in terms of a direct product of ...
Rudi Stouffs
core +1 more source

