Results 51 to 60 of about 2,232 (295)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, Volume 16, Issue 8, Page 1593-1601, August 2026.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Design and study of urban form using shape grammars [PDF]

open access: yes, 2018
The main goal of this paper is to present shape grammars as an analytical tool to study urban morphology and as a design tool for urban planning. Shape grammars emerged in the 70s through the seminal article by Stiny & Gips, and are used to analyse past ...
Sara Eloy (5995706)
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

KITOPARTS: A Virtual Playground To Explore Form, Space, & Order

open access: yesARCHive-SR, 2018
Architecture students use both analog and digital tools throughout their design process. Ideally, the affordances of each tool complement each other. Our goal with Kitoparts is to move beyond two-dimensional screen based computer modeling environments to
Derek A. Ham
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Transforming Grammars for Goal Driven Style Innovation [PDF]

open access: yes, 2007
Shape grammar transformations have been used for developing new design styles by the systematic modification of grammars that encode existing styles. We make use of a style description scheme to aid grammar transformations for goal driven style change. A
S.C. Chase, S. Ahmad
core  

Attribute Multiset Grammars for Global Explanations of Activities [PDF]

open access: yes, 2009
Recognizing multiple interleaved activities in a video requires implicitly partitioningthe detections for each activity. Furthermore, constraints between activities are impor-tant in finding valid explanations for all detections.
David Hogg   +3 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Architectural design with simple shape grammars and learning

open access: yesInteligencia Artificial, 2014
This work presents a proposal for the automatic generation of architectural design. This scheme is based on the training of simple shape grammars through reinforcement learning technics.
Eduardo Jiménez-Morales   +5 more
doaj  

Implementation issues of parallel shape grammars [PDF]

open access: yes, 2018
Shape grammars come in a variety of forms. Algebras of shapes have been defined for spatial elements of different kinds, as well as for shapes augmented with varying attributes, allowing for grammar forms to be expressed in terms of a direct product of ...
Rudi Stouffs
core   +1 more source

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