Results 131 to 140 of about 264,907 (315)

Multi-objective design optimization for high-lift aircraft configurations supported by surrogate modeling [PDF]

, 2013
Nowadays, the competition among airlines seriously depend upon the saving operating costs, with the premise that not to degrade its services quality.
Li, Daxin
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New trends in shape optimization

, 2015
This volume reflects “New Trends in Shape Optimization” and is based on a workshop of the same name organized at the Friedrich-Alexander University Erlangen-Nürnberg in September 2013.
Leugering, Günter, Pratelli, Aldo, Pratelli Aldo, Leugering Günther   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Robust Shape Optimization of Composite Structure Using Metamodels

In this work previously developed methods and original code tool KEDRO for non-deterministic optimization problems have been tested first on two truss bar problems and then applied to the shape optimization of the newcomposite pallet structure ...
Meļņikovs, Anatolijs, Januševskis, Jānis, Januševskis, Aleksandrs   +2 more
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Comparison between Gradient-free and Adjoint Based Aerodynamic Optimization of a Flying Wing Transport Aircraft in the Preliminary Design.

, 2007
This paper describes investigations of planform and shape optimizations for a flying wing transport aircraft with an Euler continuous adjoint method.
Arno, Ronzheimer, Martin, Hepperle, Widhalm, Markus   +2 more
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An Integrated Framework for Arch Dam Shape Optimization Using Stratified Conditional Sampling and Gaussian Process Surrogates

Buildings
Shape optimization of arch dams is essential for balancing structural safety and economic efficiency, yet remains computationally intensive due to costly finite element analyses and strict geometric constraints.
Qingheng Xie, Jian Wang, Yang Lu
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Steve-WV/Multi-Material-Shape-Optimization-for-Bending-and-Torsion-of-Rods: multi-material-shape-optimizatio-bending-torsion-of-rods

<p>Release for code on multi-material shape optimization for bending and torsion of rods</p ...
Steve Wolff-Vorbeck
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Metodologia para otimização topológica, dimensional e geométrica de estruturas de torres de linha de transmissão [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.Este trabalho apresenta um método de otimização topológica para torres de linha de transmissão de energia elétrica.
Rodrigues de Souza, Rafael
core