Results 121 to 130 of about 241,381 (266)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

ACCURATE REGISTRATION BETWEEN ULTRA-WIDE-FIELD AND NARROW ANGLE RETINA IMAGES WITH 3D EYEBALL SHAPE OPTIMIZATION. [PDF]

Proc Int Conf Image Proc, 2023
Zhang J, Wen B, Kalaw FGP, Cavichini M, Bartsch DG, Freeman WR, Nguyen TQ, An C.   +7 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Genetic algorithm shape optimization to manipulate the nonlinear response of a clamped-clamped beam. [PDF]

Heliyon, 2022
Mollik T, Geng Y, Shougat MREU, Fitzgerald T, Perkins E.   +4 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

PSO-Incorporated Hybrid Artificial Hummingbird Algorithm with Elite Opposition-Based Learning and Cauchy Mutation: A Case Study of Shape Optimization for CSGC-Ball Curves. [PDF]

Biomimetics (Basel), 2023
Chen K, Chen L, Hu G.
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Design and Shape Optimization of Strain Gauge Load Cell for Axial Force Measurement for Test Benches. [PDF]

Sensors (Basel), 2022
Al-Dahiree OS, Tokhi MO, Hadi NH, Hmoad NR, Ghazilla RAR, Yap HJ, Albaadani EA.   +6 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Designing high-efficiency extended depth-of-focus metalens via topology-shape optimization. [PDF]

Nanophotonics, 2022
Zheng Y, Xu M, Pu M, Zhang F, Sang D, Guo Y, Li X, Ma X, Luo X.   +8 more
europepmc   +1 more source