Results 171 to 180 of about 1,014,609 (340)

Multiparameter Shape Optimization

open access: yes, 2010
Optimization tools in engineering design often require a high computational cost. This cost originates from two main sources: First, the evaluation of the objective function involved in such problems is in general very expensive. Then, depending on the method employed and on the dimension of the design vector, the optimization procedure requires a high
Benzaoui, Abderrahmane   +1 more
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

A Computational Multiscale Framework for Bone Remodeling: Coupling Apparent Density Evolution and Microscale Shape Optimization. [PDF]

open access: yesInt J Numer Method Biomed Eng
Vemparala B   +9 more
europepmc   +1 more source

1005 Low CD Body Shape in Low Re Domain by Topology Optimization and Verification Experiment

open access: bronze, 2012
Takumi HAYASHIGUCHI   +6 more
openalex   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Mn2+-doped MgGeO3 nanophosphors with controlled shape and optimized persistent luminescence

open access: hybrid, 2023
Daniel González‐Mancebo   +3 more
openalex   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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