Mathematics, 2020 The local controlled generalized H-Bézier model is one of the most useful tools for shape designs and geometric representations in computer-aided geometric design (CAGD), which is owed to its good geometric properties, e.g., symmetry and shape adjustable
Fenhong Li +3 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Stable Bose-Einstein correlations
, 2004 The shape of Bose-Einstein (or HBT) correlation functions is determined for the case when particles are emitted from a stable source, obtained after convolutions of large number of elementary random processes.
Csorgo, T., Hegyi, S., Zajc, W. A.
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
G2 continuity conditions for generalized Bézier-like surfaces with multiple shape parameters
Journal of Inequalities and Applications, 2017 In order to tackle the problem of shape design and shape adjustment of complex surfaces in engineering, continuity conditions between generalized Bézier-like surfaces with multiple shape parameters are studied in this paper.
Gang Hu +3 more
doaj +1 more source
Inference to shape parameter of Nash model based on dynamic transport properties of channel networks. [PDF]
Heliyon, 2022 Kim JC, Yoon YJ.
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
A Parametric Identification Method of Human Gait Differences and its Application in Rehabilitation
Applied Sciences, 2019 In order to understand the regularity of human motion, characteristic description is widely used in gait analysis. For completely expressing gait information and providing more concise indicators, parametric description is also particularly significant ...
Jing Gao +5 more
doaj +1 more source
Ridge Regression Method and Bayesian Estimators under Composite LINEX Loss Function to Estimate the Shape Parameter in Lomax Distribution. [PDF]
Comput Intell Neurosci, 2022 Yassen MF, Al-Duais FS, Almazah MMA.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source