Results 101 to 110 of about 1,975,441 (290)

Optimal parameter estimation of shaped phase objects

open access: yesPhysical Review A
We show a general method to estimate with optimum precision, i.e., the best precision determined by the light-matter interaction process, a set of parameters that characterize a phase object. The method is derived from ideas presented by Pezze []. Our goal is to illuminate the main characteristics of this method as well as its applications to the ...
Arturo Villegas   +3 more
openaire   +3 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

A Three‐Stage Partitioning Framework for Modeling Mean Annual Groundwater Evapotranspiration

open access: yesWater Resources Research
An analytical model is developed for mean annual groundwater evapotranspiration (GWET) at the watershed scale based on a three‐stage precipitation partitioning framework.
Fanzhang Zeng   +5 more
doaj   +1 more source

保形分段三次多项式曲线的形状分析(Construction and analysis of a new class of shape-preserving piecewise cubic polynomial curves)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2018
This paper proposes a new class of shape-preserving piecewise cubic polynomial curves with both local and global shape control parameters. By presetting the properties of its basis functions and then solving equations,a set of polynomial basis functions ...
YANLanlan(严兰兰)   +1 more
doaj   +1 more source

Seasonal Wind Energy Characterization in the Gulf of Mexico

open access: yesEnergies, 2019
In line with Mexico’s interest in determining its wind resources, in this paper, 141 locations along the states of the Gulf of Mexico have been analyzed by calculating the main wind characteristics, such as the Weibull shape (c) and scale (k ...
Alberto-Jesus Perea-Moreno   +2 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

A New Radial Basis Function Approach Based on Hermite Expansion with Respect to the Shape Parameter

open access: yesMathematics, 2019
Owing to its high accuracy, the radial basis function (RBF) is gaining popularity in function interpolation and for solving partial differential equations (PDEs).
Saleh Abobakur Bawazeer   +2 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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