Results 141 to 150 of about 451,392 (314)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
A Note on Weighted Least-squares Estimation of the Shape Parameter of the Weibull Distribution
, 2009 This study proposes an alternative to the weighted least-squares (WLS) procedure for estimating the shape parameter of the Weibull distribution. Bergman (Journal of Materials Science Letters 1986; 5:611–614), Faucher and Tyson (F&T) (Journal of Materials
Lu, H. L.; Chen, C. H.; 吳忠武; Wu, Jong-wuu
core +1 more source
Applied Medical Informatics, 2017 Power spectral analysis of short-term heart rate variability (HRV) can provide instant valuable information to understand the functioning of autonomic control over the cardiovascular system. In this study, an adaptive continuous Morlet wavelet transform (
Ram Sewak SINGH +2 more
doaj
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Cumulative Prospect Theory and the St.Petersburg Paradox [PDF]
We find that in cumulative prospect theory (CPT) with a concave value function in gains, a lottery with finite expected value may have infinite subjective value. This problem does not occur in expected utility theory.
Rieger, Marc Oliver, Wang, Mei
core
Minimax Shrunken Technique for Estimate Burr X Distribution Shape Parameter
, 2018 The present paper concern with minimax shrinkage estimator technique in order to estimate Burr X distribution shape parameter, when prior information about the real shape obtainable as original estimate while known scale parameter. ...
Maymona M. Ameen +2 more
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
An iterative method for parameter identification and shape reconstruction
, 2010 An iterative strategy for the reconstruction of objects buried in a medium and the identification of their material parameters is analysed. The algorithm alternates guesses of the domains using topological derivatives with corrections of the parameters ...
Rapún Banzo, María Luisa +1 more
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